Companies
Startup biotech companies are among the top bio companies moving rapidly to advance novel medicines for the benefit of patients, using advanced molecular biology, tools and technologies to solve the most complex health care problems. In the last year, top biotech companies have increased investment in their research and development capabilities to stay competitive with the largest biotech companies.
Many top biotech companies in the startup list are using new technologies such RNA interference, gene editing, and gene and cell therapies to develop treatments that are more effective and safer than any previously developed. Some of them may even offer a cure for genetic disease that are otherwise deadly.
This has not gone unnoticed by the largest biotech companies, which are partnering and developing their own genetic medicines that have potential to improve health and the quality of life.
The strong capital markets in 2020 and 2021 led to a large influx in venture capital funds and strong increase in funding for startup biotech companies.
The pandemic also put both startups and the largest biotech companies in the media spotlight. The good news is that we are already witnessing the results of the top bio companies’ R&D efforts with the recent marketing approval of several genes and cell therapies. That’s why we have created a startup list of the top biotech companies in the last few years with the most significant advances in biotechnology.
| Company Link | City | State | Business | |
|---|---|---|---|---|
| 1859 | San Diego | CA | In Silico Drug Design | |
| 180 Life Sciences | Menlo Park | CA | Cannabinoids | |
| 1910 Genetics | Boston | MA | Computational chemistry platform to develop small molecule therapeutics | |
| 20n Bio | Malvern | PA | Computational Synthetic Biology | |
| 2seventy Bio | Cambridge | MA | Immuno-oncology | |
| 3Spine | Chattanooga | TN | Lumbar Joint Replacement | |
| 3T Biosciences | South SF | CA | TCR Therapies | |
| 64x Bio | San Francisco | CA | High throughput discovery and design of enhanced cell lines for next-generation biomanufacturing and therapeutics | |
| 858 Therapeutics | San Diego | CA | Precision Oncology | |
| 89bio | San Francisco | CA | Liver Treatments | |
| A2 Biotherapeutics | Agoura Hills | CA | Immunotherapy | |
| Aadi Bioscience | Los Angeles | CA | Nanoparticle albumin-bound sirolimus | |
| A-Alpha Bio | Seattle | WA | Yeast-based Drug Assay | |
| Aardvark Therapeutics | San Diego | CA | Obesity & Genetic Metabolic Disorders | |
| Aarvik Therapeutics | Fremont | CA | Antibody-Drug Conjugates | |
| AAVnerGene | North Bethesda | MD | Recombinant AAV for gene therapy, CDMO for AAV packaging | |
| Ab Studio | Hayward | CA | Antibody humanization and optimization service | |
| Abalone Bio | Richmond | CA | Antibody Therapies | |
| Abata Therapeutics | Cambridge | MA | Treg Cell Therapies | |
| Abintus Bio | San Diego | CA | Gene Therapy | |
| Ablaze Pharmaceuticals | San Diego | CA | Targeted Radiotherapy | |
| Abound Bio | Pittsburgh | PA | Therapeutic Antibody Discovery | |
| Accent Therapeutics | Lexington | MA | RNA-modifying protein inhibitors | |
| AcelaBio | San Diego | CA | Histopathology and Precision Medicine Services for Global Clinical Trials | |
| Acelyrin | Los Angeles | CA | Antibody Mimetic | |
| Acenxion Biosystems | Kansas City | KS | Direct Detection of Microbes | |
| Aclipse Therapeutics | Radnor | PA | Small Molecules | |
| Acrivon Therapeutics | Watertown | MA | Checkpoint Inhibitor | |
| Acrotech Biopharma | East Windsor | NJ | Specialty Pharmaceuticals | |
| Activ Surgical | Boston | MA | Surgical Software | |
| Actualize Therapy | Chicago | IL | Mobile Tech for Depression and Mental Illness | |
| Actym Therapeutics | Berkeley | CA | Microbial-based immunotherapy platform | |
| Acuity Spatial Genomics | Watertown | MA | Spatial 3D Genomics | |
| AcureX Therapeutics | San Carlos | CA | Neurodegenerative Treatments | |
| Acworth Pharmaceuticals | Cambridge | MA | Cancer Therapies | |
| Adagio Therapeutics | Waltham | MA | Antibodies | |
| Adanate | La Jolla | CA | Antibody Therapies | |
| Adari Cell Science | Oakland | CA | Cell-based Assays | |
| ADARx | San Diego | CA | RNA Therapeutics | |
| Adcentrx Therapeutics | San Diego | CA | Antibody drug conjugate | |
| Adipo Therapeutics | Indianapolis | IN | Polymer-based, Notch-inhibiting nanoparticles | |
| Aditx Therapeutics | Richmond | VA | Immune System Diagnosis | |
| Adlon Therapeutics | Stamford | CT | Small Molecules | |
| Adona Medical | Campbell | CA | Device for Heart Failure | |
| Advaite | Chicago | IL | Repurposed Small Molecule | |
| Advanced NanoTherapies | Los Gatos | CA | Nanoparticle technologies that enable and improve drug uptake and retention into the cell for medical devices | |
| Advanced Process Systems | St. Petersburg | FL | Advanced Process Systems – APS – upstream/downstream process consultants-design/build/rapid deployment bioreactor lab, pilot or industrial systems-CGMP-ISO 17025 Supply/integrate/calibrate: Sonotec flow meters; Brooks MFCs-BlueSens off-gas; Hamilton; Chemglass; Securecell: On-site maint – repair – calibrations:925.528.9314 | |
| Advanced Process Systems | Stafford | TX | Advanced Process Systems – APS – upstream/downstream process consultants-design/build/rapid deployment bioreactor lab, pilot or industrial systems-CGMP-ISO 17025 Supply/integrate/calibrate: Sonotec flow meters; Brooks MFCs-BlueSens off-gas; Hamilton; Chemglass; Securecell: On-site maint – repair – calibrations:925.528.9314 | |
| Advanced Process Systems | Pleasanton | CA | Advanced Process Systems – APS – upstream/downstream process consultants-design/build/rapid deployment bioreactor lab, pilot or industrial systems-CGMP-ISO 17025 Supply/integrate/calibrate: Sonotec flow meters; Brooks MFCs-BlueSens off-gas; Hamilton; Chemglass; Securecell: On-site maint – repair – calibrations:925.528.9314 | |
| Advanced Solutions Life Sciences | Louisville | KY | Tissue Handling Products, Services | |
| Aegis Life | San Diego | CA | Vaccines & Therapeutics | |
| Aerium Therapeutics | Boston | MA | Antibody, Small Molecules for Covid | |
| Aerovate Therapeutics | Boston | MA | Inhaled Version of Imatinib | |
| Aether Biomachines | Menlo Park | CA | Enzyme engineering, enabling customers to manufacture complex & novel products at fractional cost. | |
| AffaMed Therapeutics | New York | NY | ||
| Affinia Therapeutics | Waltham | MA | Gene Delivery | |
| Agastiya Biotech | Bonsall | CA | Small Molecules | |
| AgeX Therapeutics | Alameda | CA | Pluripotent stem cell-derived progenitor cell lines | |
| Agulos Biotech | Lake Mills | WI | Replacement for Fetal Bovine Serum | |
| AiM Medical Robotics | Fort Lauderdale | FL | MRI-compatible intraoperative robotics | |
| Aimmax Therapeutics | Durham | NC | Biopharmaceuticals | |
| Ainnocence | Sacramento | CA | Self-evolving AI platform for drug discovery | |
| Akdys | Durham | NC | Data-Led Pharma & Biotech Advising Firm for Innovators, CMO/CDMOs & Investors thru their life cycle | |
| Akero Therapeutics | South SF | CA | NASH therapy | |
| Akouos | Boston | MA | Gene Therapy for Hearing Disorders | |
| Alamar Biosciences | Fremont | CA | Proteomic Liquid Biopsy Platform | |
| Alercell | Bozeman | MT | Molecular Diagnostics | |
| Alessa Therapeutics | San Carlos | CA | Local delivery of anti-androgen therapy | |
| Aligos Therapeutics | South SF | CA | Therapies for hepatologic diseases and viral infections | |
| AlivaMab Discovery Services | San Diego | CA | Antibody Discovery Services | |
| Alladapt Immunotherapeutics | Menlo Park | CA | Oral Food Allergy Immunotherapies | |
| Allay Therapeutics | Menlo Park | CA | Multi-week Localized Pain Management | |
| AllerGenis | Hatfield | PA | Food Allergy Diagnostics | |
| Alleviant Medical | Austin | TX | Medical Device for Heart Failure | |
| Allievex | Marblehead | MA | Novel Therapies for the Treatment of Rare Pediatric Neurodegenerative Diseases | |
| Allogene Therapeutics | South SF | CA | CAR-T | |
| Alloplex Biotherapeutics | Woburn | MA | Cell Therapies | |
| Allorion Therapeutics | Natick | MA | Small molecule drugs against cancer and autoimmune diseases | |
| Alloy Therapeutics | Lexington | MA | Antibody Discovery Platform | |
| Allterum | Houston | TX | Monoclonal Antibody | |
| Alltrna | Cambridge | MA | tRNA therapies | |
| Almon Therapeutics | Irvine | CA | Neurodegenerative Therapies | |
| Alpenglow Biosciences | Seattle | WA | 3D spatial analysis of tissue samples | |
| Alphageneron Pharmaceuticals | Cambridge | MA | Natural Killer Therapy | |
| Alphazyme | Jupiter | FL | Custom Enzymes | |
| Alphyn Biologics | Cincinnati | OH | Topical Plant-derived treatment | |
| Alphyn Biologics | Annapolis | MD | Topical Plant-derived treatment | |
| Alpine Biotherapeutics | San Diego | CA | Stem-cell based ophthalmology treatment | |
| Altavant Sciences | Cary | NC | Small Molecules | |
| Altay Therapeutics | San Francisco | CA | Small molecules for liver disease and cancer | |
| Alterome Therapeutics | San Diego | CA | Oncology Treatments | |
| Altesa Biosciences | College Park | GA | Respiratory antiviral therapies | |
| AltiBio | Half Moon Bay | CA | Drugs | |
| Alto Neuroscience | Los Altos | CA | AI-derived brain biomarkers for therapeutic matching | |
| Altos Labs | San Francisco | CA | Cellular Rejuvenation | |
| Altus Life Science | San Jose | CA | Diagnostics & Genetic Tests | |
| Alume Biosciences | San Diego | CA | Nerve Illumination Technology | |
| Alumis | South SF | CA | Autoimmune Treatments | |
| Alyve Medical | Denver | CO | Motion-activated Stimulation Technology | |
| Amador Bioscience | Midlothian | VA | Consulting, Lab Service, Clinical Trial Management | |
| Amador Bioscience | Pleasanton | CA | Consulting, Lab Service, Clinical Trial Management | |
| AmbAgon Therapeutics | South SF | CA | Small molecule cancer drugs that stabilize the direct interaction of oncogenic proteins with the 14-3-3 class of adaptor proteins | |
| Amberstone Biosciences | Laguna Hills | CA | Solid Tumor Therapies | |
| Ambulero | Miami | FL | Cell & Gene Therapies | |
| Amide Tech | Cambridge | MA | Peptide Synthesis | |
| AmMax Bio | Redwood City | CA | Anti-CSF1 Monoclonal Antibody | |
| Ampac Analytical | El Dorado Hills | CA | Analytical development of cGMP Intermediates, APIs, and Drug Products | |
| Amplify Surgical | Laguna Hills | CA | Dual expanding interbody fusion system | |
| AmplifyBio | West Jefferson | OH | Contract Research | |
| AN2 Therapeutics | Menlo Park | CA | Novel medicines targeting infectious diseases | |
| Anavasi Diagnostics | Seattle | WA | Covid Diagnostics | |
| Ancilia Biosciences | New York | NY | CRISPR for Live Therapeutics | |
| Andelyn Biosciences | Columbus | OH | Cell & Gene Therapy CDMO | |
| Anebulo Pharmaceuticals | Austin | TX | Cannabinoid Overdose | |
| AnelleO | Chapel Hill | NC | 3D Printed Intravaginal Ring | |
| Anji Pharmaceuticals | Cambridge | MA | High-value targets validated by human genetics | |
| Ankyra Therapeutics | Boston | MA | Cytokine Immunotherapies | |
| Anodyne Nanotech | Boston | MA | Nanotech for Drug Delivery | |
| Ansa Biotechnologies | Emeryville | CA | Next Generation DNA Synthesis | |
| Anthos Therapeutics | Cambridge | MA | Antibody Therapeutics | |
| Anumana | Cambridge | MA | AI ECG reading | |
| Anuncia | Lowell | MA | Hydrocephalus Treatment | |
| Anwita Biosciences | San Carlos | CA | Antibodies & Fusion Proteins | |
| AnX Robotica | Pleasanton | CA | Medical Device Capsules | |
| AnX Robotica | Plano | TX | Medical Device Capsules | |
| ApexQubit | Berkeley | CA | microRNA & mRNA | |
| Apic Bio | Cambridge | MA | Gene Therapy | |
| Aplos Medical | Eden Prairie | MN | Implant to prevent acid-reflux | |
| Apnimed | Cambridge | MA | Sleep Apnea Drugs | |
| Apostle Inc | San Jose | CA | Cancer Diagnostics | |
| Appello Pharmaceuticals | Nashville | TN | Novel positive allosteric modulators of the metabotropic glutamate receptor subtype 4 | |
| Appia Bio | Los Angeles | CA | Cell Therapy | |
| APstem Therapeutics | Fremont | CA | Stem Cell Technology | |
| Aqua Medical | Santa Ana | CA | Vapor-Based Endoscopic Ablation Therapy | |
| Aramis Biosciences | Medfield | MA | Immuno-ophthalmology | |
| Arcutis Biotherapeutics | Westlake Village | CA | Reformulated, Topical Dermatology Products | |
| Argá Medtech | San Diego | CA | Cardiac Ablation System | |
| Arkuda Therapeutics | Watertown | MA | Small Molecule for Dementia | |
| Armas Pharmaceuticals | Manalpan Township | NJ | Generic Pharmaceuticals | |
| Aro Biotherapeutics | Philadelphia | PA | Protein Scaffolds | |
| Arpeggio Biosciences | Boulder | CO | AI Drug Screening Platform | |
| Arrakis Therapeutics | Waltham | MA | RNA-targeted small molecules | |
| Arranta Bio | Watertown | MA | CDMO | |
| ArriVent Biopharma | Newtown Square | PA | Small Molecule | |
| ARS Pharmaceuticals | San Diego | CA | Nasal Spray Epinephrine | |
| Arsenal Biosciences | South SF | CA | Cancer Treatments | |
| Arthrosi Therapeutics | San Diego | CA | Treatments for gout and chronic kidney diseases | |
| Artisan Bio | Louisville | CO | Cell Engineering | |
| Artiva Biotherapeutics | San Diego | CA | NK Cell Therapies for Cancer | |
| Artizan Biosciences | New Haven | CT | Microbiota-targeted therapies | |
| Aruvant Sciences | New York | NY | Gene Therapy | |
| Asalyxa Bio | Southfield | MI | Microparticle-based immune cell targeting therapy. | |
| Asegua Therapeutics | Foster City | CA | Authorized Gilead Generics | |
| Asimov | Boston | MA | Synthetic Biology | |
| Aspargo Laboratories | Englewood Cliffs | NJ | Oral Sildenafil | |
| Aspen Neuroscience | San Diego | CA | Personalized Regenerative Medicine | |
| Astrolabe Diagnostics | Fort Lee | NJ | Cloud-based solution for single-cell data analysis | |
| Ataia Medical | Silver Spring | MD | Verbal Communication System | |
| Atalanta Therapeutics | Boston | MA | RNAi therapeutics | |
| Atavistik Bio | Cambridge | MA | High-throughput screening platform to identify allosteric modulators of proteins | |
| Atengen | Los Angeles | CA | Small Molecules, Antibody Therapies | |
| atHeart Medical | Mountain View | CA | Device for closure of atrial septal defects | |
| Athos Therapeutics | Torrance | CA | AI-Based Precision Therapeutics | |
| AtlasXomics | New Haven | CT | Spatial imaging technique for genomics | |
| Atrility Medical | Madison | WI | Arrhythmia Monitoring | |
| Atsena Therapeutics | Durham | NC | Gene Therapy | |
| Attralus | South SF | CA | Amyloidosis Treatments | |
| Attune Neurosciences | Menlo Park | CA | Non-invasive neurostimulation products | |
| August Bioservices | Nashville | TN | Research & Development Services | |
| Aurion Biotech | Seattle | WA | Ocular Transplant Therapies | |
| Auris AI | Minneapolis | MN | Smart stethoscope | |
| Auron Therapeutics | Wellesley | MA | Differentiation Therapy | |
| Aurora Biolabs | San Diego | CA | Recombinant Research Proteins | |
| Aust Business Solutions | Knoxville | TN | Biopharma, med device, operations & manufacturing, quality system, and regulatory affairs consulting | |
| Autobahn Therapeutics | San Diego | CA | Remyelination program for multiple sclerosis | |
| Autonomous Therapeutics | Rockville | MD | Evolving Therapeutics for Lifelong Protection | |
| Autonomous Therapeutics | New York | NY | Evolving Therapeutics for Lifelong Protection | |
| Avenge Bio | Natick | MA | Cell & Gene Therapies | |
| Aviceda Therapeutics | Cambridge | MA | Next generation of glyco-immune therapeutics | |
| Avilar Therapeutics | Waltham | MA | Extracellular Targeted Protein Degradation | |
| Avior Bio | Cary | NC | Buccal Delivery via film | |
| Avisi Technologies | Philadelphia | PA | Nanotechnology-enabled implant that controls intraocular pressure in the eye to treat open-angle glaucoma | |
| Avive Solutions | San Francisco | CA | Automated External Defibrillator | |
| AxisPharm | San Diego | CA | Bioanalytical Services, Proteomics, ADC Linker and Bioconjugation Services | |
| axiVEND | Winter Garden | FL | Multiplex Tests & Microarrays | |
| Axonova Medical | Philadelphia | PA | Nerve Regeneration | |
| Azora Therapeutics | Los Angeles | CA | Novel small molecule new chemical entities for the treatment of autoimmune, inflammatory diseases | |
| Babson Diagnostics | Austin | TX | Diagnostic Blood Testing | |
| Bakx Therapeutics | Kingston | NY | Small molecules targeting apoptosis pathway | |
| BaroPace | Ashland | OR | Wearable Blood Pressure Monitor | |
| Baudax Bio | Malvern | PA | Specialty Pharma | |
| Beacon Biosignals | Boston | MA | AI software/electroencephalography for neuro biomarker discovery | |
| Beam Therapeutics | Cambridge | MA | CRISPR-based drug discovery | |
| Belite Bio | San Diego | CA | Oral Small Molecules | |
| BennuBio | Albuquerque | NM | Flow Cytometry Equipment | |
| Bexson Biomedical | Santa Barbara | CA | Subcutaneous Drug Delivery | |
| Bicara Therapeutics | Cambridge | MA | Dual-Action Biologics, Antibodies | |
| BigHat Biosciences | San Mateo | CA | Antibody Therapeutics | |
| BioAmp Diagnostics | San Carlos | CA | Diagnostics to counteract antibiotic resistance | |
| BioArkive | San Diego | CA | Biorepository | |
| BioID Genomics | Scottsdale | AZ | Microbial Identification | |
| Bioinformatics CRO | Niceville | FL | Customized computational biology services | |
| BioLab Sciences | Scottsdale | AZ | Autologous Skin Graft Production | |
| BioLoomics | Boulder | CO | Single Cell Protein Drug Discovery Biosensors | |
| Biomea Fusion | Redwood City | CA | Small Molecules Targeting Cancer | |
| BiomeSense | Chicago | IL | Biosensor & cloud-based software platform for gut microbiome analysis | |
| Biomotum | Portland | OR | Leg rehab and mobility device | |
| Bionavigen | Gaithersburg | MD | Consulting for the discovery, preclinical development, translational, and regulatory sciences as well as early development of new drugs through smart acquisition | |
| BiOneCure Therapeutics | Germantown | MD | Antibody-Drug Conjugates | |
| Bionovica | Jacksonville | FL | Out-license/tech-transfer and consulting | |
| BioPharma Global | Vienna | VA | FDA and EMA Regulatory Affairs consulting | |
| Bioptamers | Wilmington | DE | Personalized cancer drug delivery | |
| BioROSA Technologies | Boston | MA | Autism Diagnostics | |
| BioSapien | New York | NY | 3D printed biodegradable mesh | |
| Biosimilar Solutions | Camaceyes | PR | Biosimilars | |
| BioSkyrb Genomics | Durham | NC | Amplification Technology for Improved Genomic Sequencing | |
| Biovaxys | New York | NY | Haptenization | |
| BioXcel Therapeutics | New Haven | CT | Sublingual thin film formulation, oral small molecule | |
| Bioxytran | Newton | MA | Modified hemoglobin therapy | |
| Bipharm | Boston | MA | Chromosomal instability targeting | |
| BISC Global | South SF | CA | Bioinformatics, machine learning and artificial intelligence, statistics | |
| BISC Global | Boston | MA | Bioinformatics, machine learning and artificial intelligence, statistics | |
| Blacksmith Medicines | San Diego | CA | Human Metalloenzyme-Targeted Medicines | |
| Bloom Science | San Diego | CA | Microbiota-Based Drug Discovery | |
| Blue Note Therapeutics | San Francisco | CA | App for cancer distress | |
| Blue Water Vaccines | Norwood | OH | Flu Vaccine | |
| BlueAllele | Oakdale | MN | Gene Editing | |
| Bluejay Diagnostics | Acton | MA | POC Diagnostics | |
| BlueSphere Bio | Pittsburgh | PA | T Cell Therapy | |
| BOA Biomedical | Cambridge | MA | Rapid Universal Pathogen Diagnosis | |
| Bone Health Technologies | San Francisco | CA | Mechanical Bone Stimulation | |
| BostonGene | Waltham | MA | Biomedical Software | |
| Boundless Bio | La Jolla | CA | Cancer Treatments targeting extra-chromosomal DNA | |
| Brain Scientific | New York | NY | Portable EEG | |
| BRAINBox Solutions | Richmond | VA | Brain Injury Detection | |
| BRG Regulatory Consulting | Tampa | FL | Regulatory and product development consulting firm | |
| BrickBio | Woburn | MA | Protein Engineering, Antibody Conjugation, Services | |
| BridGene Biosciences | Sunnyvale | CA | Small molecules that drug traditionally undruggable targets | |
| Bright Path Laboratories | Kannapolis | NC | Continuous Generic Manufacturing | |
| Bright Uro | Aliso Viejo | CA | Urology Diagnostic Device | |
| BrightInsight | San Jose | CA | Digital Health Platform | |
| Brii Biosciences | San Mateo | CA | Bringing medicines to Chinese market | |
| Brii Biosciences | Durham | NC | Bringing medicines to Chinese market | |
| BriOri Biotech | Carlsbad | CA | Opioid-Free Pain Relief | |
| Broadwing Bio | South SF | CA | Antibody based drugs for blindness | |
| Brooklyn ImmunoTherapeutics | San Diego | CA | Cytokine-based Therapy | |
| BryoLogyx | Danville | CA | Bryostatins for drug life extension | |
| BYOMass | Sudbury | MA | Metabolic Therapies | |
| C2 Medical Robotics | West Lafayette | IN | Robotic tools and systems for spinal surgeries | |
| Cabaletta Bio | Philadelphia | PA | Chimeric Auto Antibody Receptors | |
| Cadex Genomics | Redwood City | CA | Liquid-based molecular assays | |
| Caelum Biosciences | Bordentown | NJ | Antibody Therapy | |
| CAGE Bio | San Carlos | CA | Deep Eutectic Ionic Liquids for Therapeutics | |
| Cage Pharma | Baltimore | MD | Cancer Treatment | |
| Calder Biosciences | Brooklyn | NY | Vaccine Immunogen Design | |
| Calviri | Phoenix | AZ | Cancer Diagnostics & Therapeutics | |
| Capienda Biotech | Carlsbad | CA | Novel Technology for Drug Discovery | |
| Capsida Biotherapeutics | Newbury Park | CA | AAV Gene Therapy | |
| Capsigen | Vancouver | WA | AAV Vectors | |
| Captivate Bio | Berlin | CT | Cell Culture Products | |
| Caraway Therapeutics | Cambridge | MA | Discovery of novel treatments for neurodegeneration, cognition and rare diseases | |
| Carbon Biosciences | Lexington | MA | Gene Therapy | |
| CardioDiagnostics | Campbell | CA | Cardiac Monitoring Services & Devices | |
| CardioDiagnostics Inc. | Chicago | IL | At-Home Cardiac Diagnostic | |
| Cardurion Pharmaceuticals | Boston | MA | Cardiovascular treatments | |
| Carisma Therapeutics | Philadelphia | PA | CAR Macrophage Immunotherapy | |
| Carlsmed | Carlsbad | CA | Surgical Workflow Platform | |
| Carnot BioSciences | New York | NY | ||
| Casana | Rochester | NY | Toilet Seat to Analyze Heart | |
| Casma Therapeutics | Cambridge | MA | Autophagy-focused Treatments | |
| CASPR Biotech | San Francisco | CA | Diagnostics platform through CRISPR | |
| Catamaran Bio | Cambridge | MA | CAR-Natural Killer Cell Therapies | |
| Cedilla Therapeutics | Cambridge | MA | Small Molecules for Undruggable Protein Targets | |
| CeleCor Therapeutics | Del Mar | CA | Heart attack treatment | |
| CelerisTx | Menlo Park | CA | Proximity-inducing compounds | |
| Cellanome | Redwood City | CA | Multiomics Platform | |
| Cellarcus Biosciences | La Jolla | CA | Extracellular Vesicle Analysis Assays | |
| Cellares | San Francisco | CA | Cell Therapy Manufacturing Technology | |
| Cellarity | Cambridge | MA | Drug Discovery, Unknown Modalities | |
| CellChorus | South SF | CA | Visual AI on Time-lapse Imaging Microscopy in Nanowell Grids | |
| Cellevolve | San Francisco | CA | Cell Therapy | |
| CellFE | Berkeley | CA | Intracellular Delivery Platform for Gene-Editing | |
| Cellino Biotech | Cambridge | MA | Cell therapies | |
| Cellstate Biosciences | Tucson | AZ | Immunoassays | |
| Celsius Therapeutics | Cambridge | MA | RNA sequencing for drug discovery, Antibody-drug conjugates | |
| Celularity | Warren | NJ | Placenta-derived stem cells | |
| Centaur Labs | Boston | MA | Medical data labeling including classification and segmentation for X-ray, CT, MRI, ultrasound, image, video, text etc. | |
| Center for Breakthrough Medicines | King of Prussia | PA | Cell Therapy Contract Research & Manufacturing | |
| Centessa Pharmaceuticals | Boston | MA | Umbrella company acquiring drug companies | |
| Century Therapeutics | Branchburg | NJ | iPSC Therapy platform | |
| Century Therapeutics | Philadelphia | PA | iPSC Therapy platform | |
| Ceptur Therapeutics | Hillsborough | NJ | U1 Adaptor Technology for RNA Therapeutics | |
| Cerevel Therapeutics | Cambridge | MA | Neuro | |
| Ceria Therapeutics | Aurora | CO | mRNA Delivery | |
| CERo Therapeutics | South SF | CA | Cellular Immunotherapy | |
| Ceruvia Lifesciences | Greenwich | CT | Neuro Treatments | |
| Chameleon Biosciences | Berkeley | CA | Gene Delivery Technology | |
| Chroma Medicine | Cambridge | MA | DNA modification therapy | |
| Chronus Health | Mountain View | CA | Portable Diagnostic Device | |
| CiRC Biosciences | Chicago | IL | Cell Therapy via ex-Vivo Small Molecule Treatment | |
| Circumvent Pharmaceuticals | Portland | OR | Batten Disease Treatment | |
| Civetta Therapeutics | Cambridge | MA | Small molecule targeting of beta-propeller domains | |
| Clade Therapeutics | Cambridge | MA | Stem Cell Therapies | |
| Clarametyx Biosciences | Columbus | OH | Antibodies | |
| Claret Bioscience | Santa Cruz | CA | NGS Library Prep | |
| Clear Creek Bio | Cambridge | MA | Small Molecule | |
| ClearB Therapeutics | Concord | MA | Hepatitis B Vaccine | |
| ClearCam | Austin | TX | Camera Cleaning Technology for Surgical Applications | |
| Cleerly | New York | NY | AI-driven Image Analysis for Coronary Health | |
| CloudCath | San Francisco | CA | Remote Catheter Monitoring Platform | |
| Clozex Medical | Wellesley | MA | Surgical Skin Closures | |
| CND Life Sciences | Pheonix | AZ | Synucleinopathy Diagnostic | |
| CNS Pharmaceuticals | Houston | TX | CNS drugs | |
| CoA Therapeutics | San Francisco | CA | Drugs targeting Coenzyme-A | |
| Code Biotherapeutics | Hatfield | PA | DNA-based Gene Therapy Vector | |
| Codetta Biosciences | Morrisville | NC | Multi-modal, multi-plex, and multi-omics technology | |
| Coeptis Therapeutics | Wexford | PA | 505(b)(2) | |
| Comanche Biopharma | Concord | MA | siRNA for Preeclampsia | |
| Concuir Consulting | Laguna Hills | CA | Management Consulting – Program and project management, project strategy and delivery, change management, quality, remediation consulting. | |
| Consegna Pharma | Pittsburgh | PA | Reformulation of Approved Therapies – 505(b)(2), Generic | |
| Constant Therapeutics | Boston | MA | Peptide Treatments | |
| Convalesce | San Francisco | CA | Stem Cell Therapy for Neurodegenerative Diseases | |
| CoraVie Medical | Minneapolis | MN | Implantable, continuous blood pressure monitor | |
| Corevigilance | Collegeville | PA | Pharmacovigilance and quality consulting for small to mid sized biotech/pharma | |
| CorVent Medical | Santa Clara | CA | Ventilators | |
| Cosette Pharmaceuticals | South Plainfield | NJ | Generics | |
| Cosette Pharmaceuticals | Lincolnton | NC | Generics | |
| Cosette Pharmaceuticals | Bridgewater | NJ | Generics | |
| Coya Therapeutics | Houston | TX | Ex-Vivo Treg Modification for ALS | |
| Cradle Genomics | San Diego | CA | Non-invasive prenatal testing | |
| Creyon Bio | San Diego | CA | Oligonucleotide-based Medicines | |
| CRISPR QC | San Diego | CA | Quality Control for CRISPR | |
| Crozet BioPharma | Devens | MA | Contract Research | |
| Cullgen | San Diego | CA | Protein Degradation Technology | |
| Curevo Vaccine | Bothell | WA | Vaccines | |
| Curie Therapeutics | Woburn | MA | Radiopharmaceuticals Targeting Cancer | |
| Curiteva | Tanner | AL | Spinal Implant | |
| Curiva | South Bend | IN | Diagnostics | |
| Curiva | Chicago | IL | Diagnostics | |
| Currax Pharmaceuticals | Morristown | NJ | Small Molecules, Specialty, Generics | |
| CurVe Consultants | Amsterdam | NY | Product development, process optimization, and project management services, as well as business management services | |
| Cyclarity Therapeutics | Novato | CA | 7-ketocholesterol Targeting | |
| Cyclerion Therapeutics | Cambridge | MA | Small Molecules | |
| CytoImmune Therapeutics | Monrovia | CA | Cancer Immunotherapy | |
| CytoImmune Therapeutics | Toa Baja | PR | Cancer Immunotherapy | |
| Cytologics | San Diego | CA | Human primary cells for biomedical research, drug discovery and diagnostic development. | |
| Cytonus Therapeutics | Columbus | OH | Cargocytes | |
| Cytosolix | New Haven | CT | ||
| CytoTronics | Boston | MA | Optics-free Imaging for Drug Discovery | |
| D2G Oncology | Mountain View | CA | ||
| Dalent Medical | Coral Gables | FL | Sinus Balloon | |
| Dalton Bioanalytics | Los Angeles | CA | Mass Spec Blood Analysis | |
| Dark Horse Consulting | Walnut Creek | CA | Cell & Gene Therapy Consulting | |
| Darwin Biosciences | Boulder | CO | Covid Diagnostic Platform | |
| Dascena | Houston | TX | Algorithms as Predictive Biomarkers | |
| Day One Biopharmaceuticals | South SF | CA | Cancer Treatments | |
| Deciduous Therapeutics | San Francisco | CA | Medicines that activate the endogenous immune mechanism responsible for the elimination of senescent cells | |
| DeepBiome Therapeutics | Allston | MA | Microbiome Drug Discovery | |
| Deepcell | Mountain View | CA | Genetic Tests | |
| Defined Bioscience | San Diego | CA | Cell culture reagents and media from defined sources | |
| Delee | CA | Benchtop device for the rapid isolation and analysis of circulating tumor cells from blood samples | ||
| Delfi Diagnostics | Baltimore | MD | Cancer Diagnostics | |
| Delix Therapeutics | Boston | MA | Psychoplastogens | |
| DEM BioPharma | Cambrige | MA | Cell Therapy Using Don’t Eat Me Signal | |
| Demetrix | Berkeley | CA | High Value Ingredients | |
| Denovicon Therapeutics | La Jolla | CA | Small Molecule Discovery | |
| Dermavant Sciences | Long Beach | CA | Small Molecules for Dermatology Indications | |
| Dermavant Sciences | Morrisville | NC | Small Molecules for Dermatology Indications | |
| DermBiont | Boston | MA | Topical Bacterial Products | |
| Design Pharmaceuticals | Cambridge | MA | Small Molecule Drug & Design | |
| Design Therapeutics | Carlsbad | CA | Drugs targeting disorders caused by nucleotide-repeat expansions | |
| Devoro Medical | Fremont | CA | Mechanical thrombectomy platform | |
| Dewpoint Therapeutics | Boston | MA | Biomolecular Condensates | |
| Diadem Biotherapeutics | Torrance | CA | Exosome Immunotherapy | |
| Dialectic Therapeutics | Dallas | TX | Protein Degradation Cancer Treatments | |
| Dianthus Therapeutics | Waltham | MA | Monoclonal Antibodies | |
| Digestome Therapeutics | San Francisco | CA | Food-derived Therapeutic Peptides | |
| Digital GxP | Hillsborough | NJ | Platform for paperless digital SOP, Protocols, Batch Records etc integrated with wearable IoT tools | |
| DiNAQOR | Laguna Hills | CA | Gene Therapy for Heart Conditions | |
| Disc Medicine | Cambridge | MA | Drugs to regulate hepcidin expression within the body | |
| DiscernDx | Palo Alto | CA | Consumer Clinical Data | |
| Diverse Biotech | Orlando | FL | Cannabidiol Based Drugs | |
| Diverse Biotech | Doylestown | PA | Cannabidiol Based Drugs | |
| DNALite Therapeutics | San Francisco | CA | Gene Therapy | |
| Doloromics | Menlo Park | CA | RNA sequencing database from human neuronal tissues for Drug Discovery | |
| Dorian Therapeutics | San Carlos | CA | Senoblocker Technology | |
| Dorna Therapeutics | Cambridge | MA | Targeted Immuno-Oncology | |
| DoubleRainbow Biosciences | Cambridge | MA | Drug discovery through genetic analysis of nature | |
| Drawbridge Health | Menlo Park | CA | Blood Draw Technology | |
| Dren Bio | Redwood City | CA | Protein Therapeutics | |
| DropGenie | Boston | MA | Automated Gene Editing | |
| DTx Pharma | San Diego | CA | siRNA Delivery | |
| Dyne Therapeutics | Waltham | MA | Antibody-Oligonucleotide Treatments for Muscle Diseases | |
| Dyno Therapeutics | Cambridge | MA | AAV Engineering | |
| Dynocardia | Cambridge | MA | Cuff-less Blood Pressure Monitor | |
| Dystrogen Therapeutics | Chicago | IL | Rare Disease Therapies | |
| Earli | South SF | CA | Early cancer biomarker detection | |
| Eclipse Bioinnovations | San Diego | CA | RNA Products & Services | |
| Eclipse Regenesis | Menlo Park | CA | Tissue-Growing Device for Short Bowel Syndrome | |
| ECM Therapeutics | Warrendale | PA | Extra-Cellular Matrix | |
| Edgewise Therapeutics | Boulder | CO | Small Molecules for Musculoskeletal Diseases | |
| Edison Oncology | Menlo Park | CA | Small Molecules, 505(b)(2) | |
| Egret Therapeutics | New York | NY | Neurological Disease Treatments | |
| Eikon Therapeutics | Hayward | CA | Single Particle Tracking | |
| Eikonizo Therapeutics | Cambridge | MA | Brain-penetrant Small Molecules | |
| Eikonoklastes Therapeutics | Cincinnati | OH | Immune conjugate technology targeting tissue factor breast cancer treatment | |
| Elastrin Therapeutics | Simpsonville | SC | Technology to develop therapeutics that render calcified tissue and organs supple again | |
| Electra Therapeutics | South SF | CA | Therapies for immunological diseases and cancer | |
| Element Biosciences | Sunnyvale | CA | Genetic analysis tools | |
| Element Biosciences | San Diego | CA | Genetic analysis tools | |
| Elevation Oncology | New York | NY | Monoclonal Antibody | |
| Elevian | Boston | MA | Blood components to fight aging | |
| Eliem Therapeutics | Redmond | WA | Treatments for neuronal Excitability Disorders | |
| Elixirgen Therapeutics | Baltimore | MD | Stem Cell Therapies | |
| Ellodi Pharmaceuticals | Lawrence Township | NJ | Specialty Pharma | |
| Elpis Biopharmaceuticals | Lexington | MA | Cellular & Biologic Therapies | |
| eLum Technologies | Fremont | CA | Medical Devices | |
| Emalex Biosciences | Chicago | IL | Tourette’s Treatment | |
| Embecta | Franklin Lakes | NJ | Diabetes Care | |
| Empirico | San Diego | CA | Genetics-Based Drug Discovery | |
| Empress Therapeutics | Cambridge | MA | Co-Evolved Medicines | |
| Empyrean Medical Systems | Boca Raton | FL | Radiotherapy Oncology System | |
| Enable Medicine | ZZ | CA | Spatial Biology | |
| EnClear Therapies | Newburyport | MA | ALS Treatment Device | |
| Endeavor BioMedicines | San Diego | CA | Hedgehog signaling pathway inhibitor | |
| Endiatx | Redwood City | CA | Pill-sized Robot | |
| EndoCyclic | Irvine | CA | Endometriosis Therapies | |
| Endovascular Engineering | Menlo Park | CA | Thrombectomy Device | |
| Endpoint Health | Palo Alto | CA | Personalized Medicine | |
| Endure Biotherapeutics | San Diego | CA | Engineered Native Bacteria | |
| Engrail Therapeutics | San Diego | CA | Treatments for Life-Limiting Diseases | |
| Enliven Therapeutics | Boulder | CO | Cancer Treatments | |
| Enosi Life Sciences | San Diego | CA | Anti-TNF therapeutics for inflammatory autoimmune diseases and cancer | |
| ENSEM Therapeutics | Medford | MA | Characterizing rare conformational states in drug targets | |
| Entrada Therapeutics | Boston | MA | Biologics delivered to cytosol | |
| Enveda Biosciences | Boulder | CO | Small Molecule Drug Discovery from Plants | |
| Enveric Biosciences | Naples | FL | Cannabinoids | |
| Epic Neuro | Fountain Valley | CA | Minimally invasive brain stimulation & cortical EEG recording for stroke recovery | |
| EpiVario | Philadelphia | PA | Small molecule inhibitor of ACSS2 | |
| EQRx | Cambridge | MA | Creating novel, cheap drugs | |
| Equillium | La Jolla | CA | Monoclonal Antibody Therapies | |
| Erasca | San Diego | CA | Cancer Therapies | |
| Erisyon | Austin | TX | Single molecule protein sequencer | |
| Escient Pharmaceuticals | San Diego | CA | GPCR-targeted Drugs | |
| EtiraRx | Dallas | TX | Oral Cancer Therapy | |
| Eton Pharmaceuticals | Deer Park | IL | 505(b)(2) drugs | |
| ETS Wound Care | Rolla | MO | Wound Healing Biomaterial | |
| Eumentis Therapeutics | Boston | MA | Novel therapeutics for the treatment of neuropsychiatric diseases | |
| Euphrates Vascular | St. Louis | MO | Percutaneous Reperfusion System | |
| Eutheria Bioscience | San Diego | CA | R&D services: in-vitro/in-vivo/ex-vivo | |
| Evergreen Theragnostics | Jersey City | NJ | Radiopharmaceutical CDMO | |
| EvoEndo | Englewood | CO | Transnasal endoscope | |
| EvolveImmune Therapeutics | Branford | CT | Novel Immunotherapy Targets | |
| Evommune | Los Altos | CA | Human Skin Model for Drug Discovery | |
| Evozyne | Chicago | IL | Protein Design Platform | |
| Exacis Biotherapeutics | Cambridge | MA | mRNA-based technology to develop engineered cell therapies for solid and liquid tumors | |
| Exai Bio | Palo Alto | CA | Liquid Biopsy | |
| Excellos | San Diego | CA | Cell & Gene Therapy CDMO | |
| Exegenesis Bio | Boston | MA | Gene Therapy | |
| Exegenesis Bio | Lower Gwynedd | PA | Gene Therapy | |
| Exelead | Indianapolis | IN | Clinical Development, Commercial & Clinical Manufacturing | |
| Exo Therapeutics | Watertown | MA | Small Molecule Drug Discovery | |
| ExonanoRNA | Columbus | OH | RNA nanoparticles, therapies | |
| Expansion Therapeutics | Jupiter | FL | Small Molecules for RNA-mediated Diseases | |
| Expansion Therapeutics | Waltham | MA | RNA Targeted Small Molecules | |
| ExpressCells | Philadelphia | PA | Custom Cell Lines | |
| f5 Therapeutics | San Diego | CA | Small-molecule, targeted protein degraders | |
| FAScinate Therapeutics | San Diego | CA | Parkinson’s Treatment | |
| Fauna Bio | Emeryville | CA | Cross-Mammalian Genomics for Human Health | |
| Faze Medicines | Cambridge | MA | Treatments for Disease-Causing Condensates | |
| FBB Biomed | Coralville | IA | Liquid Biopsy | |
| Federation Bio | South SF | CA | Design, discover, and develop robust communities of microbes | |
| Felix Biotechnology | San Francisco | CA | Targeted Biotherapeutics | |
| FerGene | Cambridge | MA | Treatment for non-muscle invasive bladder cancer | |
| Filtricine | Santa Clara | CA | Nutrition for Cancer Management, Modified Dialysis | |
| Firma Clinical Research | Hunt Valley | MD | Clinical Research | |
| Firma Clinical Research | Chicago | IL | Clinical Research | |
| Fixx Pharmaceuticals | Las Vegas | NV | Developing a cure for Hemophilia through the use of CRISPR gene editing | |
| Flare Therapeutics | Cambridge | MA | Therapeutics Targeting Transcription Factors | |
| Flightpath Biosciences | Berkeley | CA | Reformulations for Tick-borne Diseases | |
| Fluent BioSciences | Watertown | MA | Single Cell Analysis Without Complex Instrumentation | |
| Forcyte Biotechnologies | Los Angeles | CA | Automated single-cell contractility screening | |
| Foresight Diagnostics | Louisville | CO | Cancer Diagnostics | |
| Forge Biologics | Columbus | OH | Biologics | |
| Forkhead BioTherapeutics | New York | NY | Oral Diabetes Treatment | |
| Forte Biosciences | Torrance | CA | Atopic Dermatitis Treatment | |
| ForwardVue Pharma | Mobile | AL | Novel long acting ORAI1 blocker | |
| Fountain Therapeutics | South SF | CA | AI-based drug screening platform for age-related therapies | |
| Frontier Medicines | South SF | CA | Drug Discovery Using Chemoproteomics Platform | |
| G3 Pharmaceuticals | Lexington | MA | Galectin-3 Targeting | |
| Gaba Therapeutics | Newport Beach | CA | Small Molecule | |
| Galaxy Medical | San Carlos | CA | Pulsed Electric Field Device | |
| Gameto | New York | NY | Female Fertility Extension | |
| Garuda Therapeutics | Natick | MA | Off-the-shelf hematopoietic stem cell therapies | |
| Gate Neurosciences | Indianapolis | IN | ||
| GelMedix | Cambridge | MA | Biomaterials for improved drug delivery | |
| Gemelli Biotech | Los Angeles | CA | Novel diagnostics and therapeutics for the human microbiome, gut gas profile | |
| Gemini Bio-Products | West Sacramento | CA | Media, Cell Culture Products | |
| GemPharmatech | Wilmington | DE | Genetically Engineered Mouse Models | |
| GEn1E Lifesciences | Palo Alto | CA | Rare Diseases | |
| Genemod | Seattle | WA | Lab management software | |
| Geneos Therapeutics | Plymouth Meeting | PA | Plasmid-based Neoantigen-targeted Cancer Therapies | |
| Generation Bio | Cambridge | MA | Gene Therapy | |
| Genesis Drug Discovery & Development | Hamilton | NJ | Preclinical drug discovery/development as well as model development for a wide range of therapeutic areas | |
| Genesis Therapeutics | Burlingame | CA | AI Drug Discovery | |
| GeneTether | Berkeley | CA | Improving CRISPR-efficiency | |
| Genie LifeSciences | Waltham | MA | Lab Automation | |
| Gennao Bio | New Haven | CT | Nucleic Acid Therapeutics | |
| Genome Insight | La Jolla | CA | Genomic Analysis | |
| Genome Protection | Buffalo | NY | Genome Protection Treatments | |
| Genomic Prediction | North Brunswick | NJ | Genomic Testing | |
| Geocann | Fort Collins | CO | Bioavailable Cannabis | |
| GigaMune | South SF | CA | Cell Therapies for Solid Tumors | |
| Globin Solutions | Pittsburgh | PA | Heme-Based Solutions for Poisoning | |
| Glympse Bio | Cambridge | MA | Activity Sensors | |
| Glyphic Biotechnologies | San Francisco | CA | Protein Sequencing Platform | |
| Goldilocks Therapeutics | Bedford | NY | Mesoscale nanoparticles | |
| Gordian Biotechnology | San Francisco | CA | Drug Screening Platform | |
| Gossamer Bio | San Diego | CA | Small Molecules | |
| Gotham Therapeutics | New York | NY | Targeting messenger RNA-modulating proteins | |
| Grace Science | Menlo Park | CA | Small Molecules Targeting Rare Diseases | |
| Gracon Manufacturing | Lafayette | CO | Gracon Manufacturing specializes in cleanroom injection molding. Certified to ISO 13485 & 9001. | |
| Gradian Diagnostics | Miami Beach | FL | Diagnostics | |
| Granata Bio | Duxbury | MA | Fertility Treatments | |
| Graphite Bio | South SF | CA | Next Generation Gene-Editing | |
| Gravitas Medical | San Francisco | CA | Feeding Tube Monitor | |
| GRIP Molecular Technologies | Saint Paul | MN | Graphene Biosensors | |
| GT Medical Technologies | Tempe | AZ | Surgically Targeted Radiation Therapy | |
| Guardian Therapeutics | Lexington | MA | Aptamer Therapeutics | |
| Halia Therapeutics | Salt Lake City | UT | Small molecule therapeutics targeting essential mediators of inflammation | |
| Happe Spine | Grand Rapids | MI | Spinal Fusion Implant Material | |
| Harbinger Health | Cambridge | MA | Cancer Diagnostics | |
| Harmony Biosciences | Plymouth Meeting | PA | Sleep & CNS disorders | |
| Haya Therapeutics | San Diego | CA | RNA-based, RNA-targeting Fibrotic Therapies | |
| hC Bioscience | Cambridge | MA | tRNA-based Therapeutics | |
| HDT Bio | Seattle | WA | RNA delivery technology, Immune Activators (Adjuvants) | |
| Health Technology Innovations | Portland | OR | Accelerating Structure-based Drug Discovery with Cryo EM Services and Software | |
| Heligenics | Las Vegas | NV | Cell-Based Genetic Variant Libraries | |
| Hera Health Solutions | Memphis | TN | Bioerodible Drug Delivery Implants | |
| Herophilus | San Francisco | CA | Phenotypic screening to discover novel drugs for complex neurological and psychiatric diseases | |
| Hexagon Bio | Menlo Park | CA | Fungal Genomic Sequencing, Possible Therapeutic Applications | |
| HiberCell | New York | NY | Tumor dormancy detection and treatments | |
| HighPassBio | Cambridge | MA | T cell immunotherapies | |
| HilleVax | Boston | MA | Norovirus Vaccine | |
| Hinge Therapeutics | Sunnyvale | CA | AI Small Molecule Drug Discovery | |
| Holobiome | Cambridge | MA | Microbiome Therapeutics Targeting Nervous System | |
| Honeycomb Biotechnologies | Waltham | MA | HIVE scRNAseq Solution | |
| Hoth Therapeutics | New York | NY | 505(b)(2) antimicrobial | |
| HotSpot Therapeutics | Boston | MA | Small Molecules designed for Distinct Protein Domains | |
| Humabiologics | Phoenix | AZ | Services and Consulting | |
| i2O Therapeutics | Cambridge | MA | Oral Biologics | |
| iChek | Atlanta | GA | Active Contacts Lenses for Health Monitoring | |
| Ichnos Sciences | New York | NY | Bispecific Antibodies | |
| IconOVir Bio | San Diego | CA | Oncolytic Virus Therapy | |
| Icosavax | Seattle | WA | Vaccines, VLP | |
| Ictero Medical | Houston | TX | Minimallly-invasive Gallbladder Ablation | |
| iECURE | Philadelphia | PA | Gene Editing Therapies | |
| IFM Therapeutics (2) | Boston | MA | Innate Immunity Therapeutics | |
| IgGenix | South SF | CA | Allergy Antibody Therapy | |
| IGIA Pharmaceuticals | Florence | KY | Pharmaceutical products for the treatment of orphan indications or small population indications with an unmet medical need | |
| Ileo Science | Salt Lake City | UT | Nanoformulations | |
| Imbria Pharmaceuticals | Boston | MA | Partial fatty acid oxidation (pFOX) inhibitor | |
| Imbrium Therapeutics | Stamford | CT | Small Molecules | |
| iMetabolic Biopharma | Tempe | AZ | New modifications of existing drugs | |
| Immetas Therapeutics | East Hanover | NJ | Age-related Treatments | |
| ImmPACT Bio | Camarillo | CA | CAR-T | |
| ImmuneBridge | San Francisco | CA | Allogeneic immunotherapies for cancer | |
| ImmuneID | Waltham | MA | Antibody Discovery Platform | |
| Immunitas Therapeutics | Waltham | MA | Single cell genomics-based drug discovery | |
| ImmunoGenesis | Houston | TX | Immunotherapies | |
| ImmunoMind | Berkeley | CA | AI-powered platform for ultra-fast discovery of biomarkers | |
| Immunovant | Durham | NC | Monoclonal Antibody | |
| Immunowake | Birmingham | AL | Antibody-based Therapeutics | |
| ImmunSYS | Fort Lauderdale | FL | Cancer Immunotherapy with Device | |
| Inceptor Bio | Raleigh | NC | Cell & Gene Therapy Manufacturing Platform | |
| INCOG BioPharma | Fishers | IN | Injectable CDMO | |
| Incyclix Bio | Durham | NC | Precision treatments that target the aberrant proliferation driving many cancers | |
| Indapta Therapeutics | San Francisco | CA | allogeneic FcRγ-deficient natural killer cells | |
| Indee Labs | Berkeley | CA | Gene Delivery Technology | |
| Indiana Lysis Technologies | Zionsville | |||
| Infixion Bioscience | San Diego | CA | Neurofibromatosis Type 1 Treatments | |
| Inflammasome Therapeutics | Newton | MA | Therapies for prevalent, degenerative diseases as well as sustained-release drug delivery systems | |
| Ingenia Therapeutics | Cambridge | MA | Antibody Therapies | |
| Inipharm | Bellevue | WA | Liver Disease Therapies | |
| Initium Therapeutics | Natick | |||
| Innervo Technology | Chicago | IL | Balance Device | |
| Innogenix | Amityville | NY | Generics | |
| insitro | South SF | CA | Machine Learning, Drug Discovery | |
| Instapath | Houston | TX | Automated Digital Pathology | |
| Instylla | Bedford | MA | Embolization treatment | |
| Integrated Bioanalysis | Wake Forest | NC | Consulting and lab based contract research services | |
| Integrated Pharma Services | Rockville | MD | Diagnostics and therapeutics services | |
| Intera Oncology | Wellesley | MA | Oncology and Neuromodulation Drug Delivery | |
| Intergalactic Therapeutics | Boston | MA | Non-viral Gene Therapy | |
| Interline Therapeutics | South SF | CA | Precision medicine platform to map and modulate protein communities | |
| Intersect Diagnostics | New York | NY | Novel biomarker signatures for precision therapeutics | |
| InterVenn BioSciences | South SF | CA | Cancer Diagnostic | |
| Intrinsic Medicine | Seattle | WA | ||
| Invea Therapeutics | Guilford | CT | AI Drug Discovery to Target Gut-Brain Axis | |
| Invictech | Louisville | KY | Microfluidics | |
| IO Biosciences | Doylestown | PA | Gene-Modified Cell Therapy | |
| iota Biosciences | Berkeley | CA | Implantable Bioelectronic Devices | |
| Isolere Bio | Durham | NC | Chromatography-free solutions for the purification of biological therapeutics | |
| Isosceles Pharmaceuticals | Wilmington | NC | Parenteral, Non-opioid Pain Relief | |
| Iterative Scopes | Cambridge | MA | Products & Services for Gastroenterology | |
| iTOLERANCE | San Mateo | CA | Regenerative Medicines | |
| iTolerance | Miami | FL | Implants, Cell Therapy | |
| iVexSol | Worcester | MA | Lentiviral vectors | |
| JADBio | Los Angeles | CA | Machine Learning Data Analysis | |
| Jaguar Gene Therapy | Lake Forest | IL | AAV-Based Gene Therapies | |
| Janux Therapeutics | La Jolla | CA | Immunotherapies for Cancer | |
| Jasper Therapeutics | Redwood City | CA | Humanized Monoclonal Antibody | |
| Javelin Biotech | Woburn | MA | Drug Analysis Technology | |
| Jeeva Informatics | Tysons Corner | VA | eClinical SaaS platform | |
| JOINN Biologics | Richmond | CA | Biologics CDMO | |
| Journey Colab | San Francisco | CA | Psychedelics, Mescaline | |
| Juno Diagnostics | San Diego | CA | Prenatal Genetic Testing | |
| Juvena Therapeutics | Palo Alto | CA | Tissue Regeneration & Repair | |
| K36 Therapeutics | Cambridge | MA | Inhibitor of the histone methyltransferase | |
| Kainomyx | South SF | CA | Malaria and parasitic diseases | |
| KaliVir Immunotherapeutics | Pittsburgh | PA | Oncolytic vaccinia virus immunotherapies | |
| Kanvas Bioscience | Ithaca | NY | Microbial imaging technology | |
| Kartos Therapeutics | Redwood City | CA | Oral MDM2 Inhibitor | |
| Karuna Labs | San Francisco | CA | Virtual Reality for Pain Relief | |
| Karyosoft | Dallas | TX | Genomics Data Solutions | |
| KeifeRx | Mclean | VA | Tyrosine kinase inhibitors | |
| Kelonia Therapeutics | Boston | MA | in vivo CAR T Gene Therapy | |
| Kephera Diagnostics | Framingham | MA | Point-of-Care Diagnostics | |
| Khloris Biosciences | Mountain View | CA | Cancer Vaccine | |
| Kinnate Biopharma | San Diego | CA | Small Molecules | |
| Kira Pharmaceuticals | Cambridge | MA | Complement drug discovery | |
| Kojin Therapeutics | Cambridge | MA | Small molecules targeting ferroptosis | |
| Korro Bio | Cambridge | MA | RNA-editing Drugs | |
| Koutif Therapeutics | Beachwood | OH | Inflammatory Disease Treatments | |
| Koya Medical | Oakland | CA | Active continuous sequential compression treatment | |
| Kriya Therapeutics | Morrisville | NC | Gene Therapy | |
| Kriya Therapeutics | Redwood City | CA | Gene Therapy | |
| Kronos Bio | Cambridge | MA | First-in-class therapies against historically intractable targets | |
| KSL Biomedical | Buffalo | NY | Diagnostic Technology | |
| Kumquat Biosciences | San Diego | CA | Cancer Therapies | |
| Kurome Therapeutics | Cincinnati | OH | Small Molecules | |
| Kymera Therapeutics | Watertown | MA | Small Molecules acting to degrade proteins | |
| Kytopen | Cambridge | MA | Gene-modified Cell Therapies | |
| Kyverna Therapeutics | Berkeley | CA | Treg Cell Therapy for Autoimmune Diseases | |
| Lab Owl | Neptune | NJ | Bioreactor Control System for Cell Culture & Fermentation Applications | |
| Lacerta Therapeutics | Alachua | FL | AAV Capsid Gene Therapy | |
| Lactocore | Newton | MA | CNS Peptides | |
| Landos Biopharma | Blacksburg | VA | Autoimmune Treatments | |
| Lanier Biotherapeutics | Bogart | GA | Bi-functional Antibodies | |
| Larimar Therapeutics | Bala Cynwyd | PA | Small Molecules | |
| Laronde | Cambridge | MA | Plasmid RNA Therapeutics | |
| Lassen Therapeutics | San Diego | CA | Anti-IL-11 Antibodies | |
| Lassogen | San Diego | CA | Lasso peptide-based therapies | |
| LatchBio | San Francisco | CA | LatchBio is a cloud bioinformatics platform to help biological teams accelerate their R&D. Upload custom workflows or run RNA-seq, AlphaFold, CRISPRESSO2, and more. Organize, centralize, track provenance, reproduce executions, and visualize results to derive insight for your next experiment. | |
| Leal Therapeutics | Philadelphia | PA | CNS Therapies | |
| Leal Therapeutics | Worcester | MA | CNS Therapies | |
| Lento Bio | Potsdam | NY | Small-molecule therapeutics to target molecular damage driving age-related disease | |
| LevitasBio | Menlo Park | CA | Cellular Analysis using Magnetic Levitation | |
| Levo Therapeutics | Skokie | IL | Intranasal Therapy for Prader-Willi | |
| Lexeo Therapeutics | New York | NY | Gene Therapy | |
| Libra Therapeutics | San Diego | CA | Small Molecules for Neurodegenerative Indications | |
| LifeEDIT | Morrisville | NC | Gene Editing Technology | |
| LifeHealth | Roseville | MN | Blood Analysis System | |
| LifeMine Therapeutics | Cambridge | MA | Fungi-derived therapeutics | |
| LightDeck Diagnostics | Boulder | CO | Acute Care Diagnostics | |
| LikeMinds | Boston | MA | Dopamine transporter imaging-agent platform | |
| Lindsey Regulatory Affairs Consulting | Durham | NC | LRA Consulting is an RA, QA, CA consulting firm providing individualized product strategies, global product submission assistance, and so much more | |
| Lindy Biosciences | Durham | NC | Novel Drug Formulations | |
| Link Immunotherapeutics | Seattle | WA | Dual Bispecifics | |
| Linus Biotechnology | New York | NY | Biomarker Discovery | |
| LIPAC Oncology | Pomona | CA | Intravesical delivery | |
| Lipidio Pharmaceuticals | San Diego | CA | Drugs to treat diseases associated with excess body fat | |
| Longboard Pharmaceuticals | La Jolla | CA | Novel central nervous system-targeted assets | |
| LTZ Therapeutics | Palo Alto | CA | Immunotherapies | |
| LUCA Biologics | Los Angeles | CA | Treatment Targeting Vaginal Microbiome | |
| LucasPye Bio | Philadelphia | PA | Biologics CDMO | |
| Lucid Diagnostics | New York | NY | Diagnostics | |
| Lucid Scientific | Atlanta | GA | Cell Culture Monitors | |
| Luciole Pharmaceuticals | Natick | MA | Small Molecules for mitochondrial DNA repair | |
| Lucy Therapeutics | Cambridge | MA | Small molecule treatments for neurological diseases along with a unique peripheral mitochondrial biomarker | |
| Lumen Bioscience | Seattle | WA | Biologics | |
| Luminary Therapeutics | Minneapolis | MN | Non-viral Autologous Cell Therapy | |
| LunaDNA | San Diego | CA | Crowd-sourced DNA database | |
| Lupagen | Irving | TX | Improved Cell & Gene Therapy Production | |
| Lycia Therapeutics | South SF | CA | Lysosomal Targeting Chimeras Targeting Protein Degradation | |
| Lyell Immunopharma | Bothell | WA | Curative cell-based immunotherapies | |
| Lyell Immunopharma | Seattle | WA | Curative cell-based immunotherapies | |
| Lyell Immunopharma | South SF | CA | Curative cell-based immunotherapies | |
| LyGenesis | Pittsburgh | PA | Organ regeneration | |
| Lykan Bioscience | Hopkinton | MA | Contract Manufacturing – Cell-based Therapies | |
| Madera Therapeutics | Cary | NC | Small Molecule Cancer Therapies | |
| Magellan Bioanalytics | Orem | UT | Biomarker Identification | |
| Magnolia Neurosciences | Seattle | WA | Neuroscience | |
| Mahana Therapeutics | San Francisco | CA | App for IBS | |
| MAIA Biotechnology | Chicago | IL | Peptide Cancer Therapies | |
| Mammoth Biosciences | Brisbane | CA | Diagnostics using CRISPR, Gene-Editing Therapies | |
| MANA Therapeutics | Waltham | MA | Off-the-shelf allogeneic cell therapies | |
| Manifold Bio | Boston | MA | Measurement-driven drug design | |
| Mantle Biotech | Cambridge | MA | Extremophile Proteins for Diagnostics | |
| MapLight Therapeutics | Boston | MA | Optogenetics | |
| Marpē Therapeutics | Snellville | GA | Anti Virals | |
| Marrow Access Technologies | Minnetonka | MN | Marrow Access Device | |
| Martin Pharmaceuticals | New York | NY | Repurposing drugs | |
| MassMatrix | Columbus | OH | NextGen Protein and Peptide Data Analysis Solutions | |
| Matica Biotechnology | College Station | TX | CDMO for Cell, Gene, Vaccines & Viral Therapies | |
| Maxygen (2) | Sunnyvale | CA | Directed evolution services for protein engineering | |
| MayTrex Therapeutics | Milford | MA | Therapies Targeting Extracellular Matrix | |
| Maze Therapeutics | South SF | CA | Genetic Modifiers of Disease | |
| MBX Biosciences | Carmel | IN | Hormone Analogues for Rare Endocrine Diseases | |
| Meadowhawk Biolabs | Hayward | CA | Small & Large Molecule CRO | |
| Meadowhawk Biolabs | Marlborough | MA | Small & Large Molecule CRO | |
| Mediar Therapeutics | Cambridge | MA | ||
| Meitheal Pharmaceuticals | Chicago | IL | Generics | |
| Mekonos | San Francisco | CA | Automated-System-On-A-Chip | |
| Melt Pharmaceuticals | Nashville | TN | Sublingual Delivery of sedatives | |
| Melzi Surgical | Reno | NV | Surgical Sharps Finder | |
| Mercy BioAnalytics | Natick | MA | Early cancer detection based on analysis of single extracellular vesicles | |
| MetasTx | Basking Ridge | NJ | Treatments for Metastatic Prostate Cancer | |
| Metavant Sciences | Raleigh | NC | Small Molecules for Diabetes | |
| MetVital | San Diego | CA | Small Molecule | |
| Mezomax | San Francisco | CA | Oral Treatment for Bone Fracture | |
| Micronoma | San Diego | CA | Cancer Biomarker Diagnostics | |
| MindRhythm | Cupertino | CA | Headset for Stroke Triage | |
| MindX Sciences | Indianapolis | IN | Depression Diagnostic | |
| Mineralys Therapeutics | Radnor | PA | Small Molecules | |
| MiNK Therapeutics | Lexington | MA | Cell Therapy, CAR-T | |
| Minutia | Oakland | CA | Cell Therapy – Diabetes | |
| Mirum Pharmaceuticals | Foster City | CA | Small Molecules | |
| Molecular Depot | San Diego | CA | Antibodies, Development | |
| MOMA Therapeutics | Boston | MA | Enzymes – Molecular Machines | |
| Monopteros Therapeutics | Boston | MA | Oncology Small Molecule | |
| Moonlight Therapeutics | Atlanta | GA | Allergy treatments | |
| Morari Medical | Maple Grove | MN | Neuromodulation to prevent Premature Ejaculation | |
| Moray Medical | Mountain View | CA | Catheter Control Technology | |
| MorphImmune | San Francisco | CA | Small molecule targeting ligands for delivering immunomodulating drugs | |
| Mozart Therapeutics | Seattle | WA | CD8 Treg cell modulators | |
| Mycovia Pharmaceuticals | Durham | NC | Women’s Health | |
| Mycrodose Therapeutics | San Diego | CA | Psychedelic Drug Delivery | |
| Myeloid Therapeutics | Cambridge | MA | Cell Therapy for Cancer | |
| Myosana Therapeutics | Scottsdale | AZ | Non-viral Gene Therapy | |
| Mytide Therapeutics | Boston | MA | Peptide Manufacturing Platform | |
| MZ Biolabs | Tucson | AZ | Mass Spec Services | |
| Nabla Bio | Boston | MA | Antibody Design | |
| Nammi Therapeutics | Los Angeles | CA | Nanocarriers Targeting Tumors | |
| NanoCell Therapeutics | King of Prussia | PA | Gene Therapy | |
| NanoFUSE Biologics | Malden | MA | Bioactive glass combined with DBM | |
| Nanopec | Tucson | AZ | Bio-photonic film that enhances in vitro diagnostic signals | |
| Nanoscope Therapeutics | Bedford | TX | AAV-delivered opsin | |
| NanoTech Pharma | Hillsborough | NJ | Generics, 505(b)(2) | |
| Nanotein | El Cerrito | CA | Next-gen CAR-T Cell Activation & Expansion | |
| Nashville Biosciences | Nashville | TN | Linked EMR and biospecimens | |
| NAVAN Technologies | San Carlos | CA | Cellular Transfection Technology | |
| Navega Therapeutics | San Diego | CA | Chronic Pain Treatment | |
| Naveris | Natick | MA | Cancer Diagnostic | |
| Navigation Sciences | Brookline | MA | Surgical Navigation | |
| Navire Pharma | San Francisco | CA | Small Molecules Targeting SHP2 | |
| Navrogen | Cheyney | PA | Humoral Immuno-Oncology | |
| Nebula Genomics | San Francisco | CA | Consumer Sequencing, Blockchain, Selling Personal Data, George Church, etc | |
| Nectero Medical | Tempe | AZ | Endovascular Aneurysm Stabilization Treatment | |
| NellOne Therapeutics | Knoxville | TN | Signaling Protein | |
| Neoleukin Therapeutics | Seattle | WA | Neoleukins | |
| NeoProgen | Baltimore | MD | Exosomes derived from immortal neonatal stem cells | |
| NephroDi Therapeutics | Philadelphia | PA | Small molecule for concentration disorders of the kidney | |
| Nereid Therapeutics | BOSTON | MA | Small molecules that can modulate protein interactions found in disease states | |
| NeuBase Therapeutics | Pittsburgh | PA | Oligonucleotides | |
| Neumentum | Palo Alto | CA | Non-opioid analgesic and neurology specialty pharmaceutical company | |
| Neumora Therapeutics | South SF | CA | Precision Medicines for Brain Diseases | |
| Neumora Therapeutics | Watertown | MA | Precision Medicines for Brain Diseases | |
| NeuraLace Medical | San Diego | CA | Nerve Stimulation for Pain Management | |
| Neuraly | Gaithersburg | MD | PEGylated Small Molecule | |
| neuro42 | San Francisco | CA | MRI, Robotic/AI platform | |
| NeuroBo Pharmaceuticals | Boston | MA | CNS & Diabetic Neuropathic Pain Treatments | |
| Neurocarrus | Lincoln | NE | Non-opioid pain relief | |
| NeuroDex | Natick | MA | Brain Diagnostics | |
| Neurogene | Houston | TX | Genetic Therapies | |
| Neurogene | New York | NY | Genetic Therapies | |
| Neuron23 | South SF | CA | AI-drug discovery | |
| Neuroptika | Cambridge | MA | Regenerative Treatments for Ophthalmic Diseases | |
| NeuScience | San Antonio | TX | Computer vision to detect phenotypic signals, resulting in novel, pan-cancer biomarkers | |
| Neutrolis | Cambridge | MA | Enzyme Analogue Inflammation Treatment | |
| Neuvogen | San Diego | CA | Whole-cell Cancer Vaccines | |
| NewLimit | South SF | CA | Epigenetic Reprogramming Therapies | |
| Newormics | Austin | TX | Large Scale Screening Platform for Nematodes | |
| NexEos Bio | Pottstown | PA | Diagnosis of eosinophil-related inflammatory diseases | |
| Nexien BioPharma | Denver | CO | Cannabinoids | |
| Next Generation Clinical Research | Fitchburg | WI | Clinical Research | |
| Nextbiotics | Oakland | CA | Bacteriophage Therapy | |
| Nextgen BioX | Lewes | DE | Artificial Human Organs | |
| NextRNA Therapeutics | Cambridge | MA | Treatments Targeting Non-Coding RNA | |
| NiKang Therapeutics | Wilmington | DE | Small Molecules for Oncology | |
| Nimble Therapeutics | Madison | WI | Photoprotected Amino Acids | |
| Nine Square Therapeutics | South SF | CA | Small Molecules for Neuro | |
| NJ Biopharmaceuticals | Princeton | NJ | Contract Research | |
| NKGEN Biotech | Santa Ana | CA | Autologous and allogenic Natural Killer cell therapy | |
| Nocion Therapeutics | Waltham | MA | Nocions which preferentially target activated sensory neurons that are responding to external insult | |
| Noeledge | Monroe | WA | Consultant offering marketing services to various businesses in the healthcare sector | |
| Nooma Bio | Santa Cruz | CA | Nanopores to control and map genomic and epigenetic features on single molecules of high molecular weight DNA | |
| NOTA Labs | Ann Arbor | MI | Nitric Oxide | |
| Notitia Biotechnologies | Monmouth Junction | NJ | Microbiome | |
| Novilla Pharmaceuticals | Cambridge | MA | Drug delivery technology for local administration of pain relief | |
| Novilla Pharmaceuticals | Arlington | VA | Drug delivery technology for local administration of pain relief | |
| Novosteo | West Lafayette | IN | Fracture-Targeted Drug Delivery | |
| Nucleai | Chicago | IL | AI-powered Tumor Micro Environment modeling | |
| Nuclein | Austin | TX | Handheld PCR Diagnostics | |
| Nura Bio | South SF | CA | Small Molecule | |
| Nutcracker Therapeutics | Emeryville | CA | mRNA manufacturing device | |
| Nuvalent | Cambridge | MA | Structure-based Drug Design for Kinase Targeting | |
| Nuvation Bio | San Francisco | CA | Oncology Treatments | |
| Nuvation Bio | New York | NY | Oncology Treatments | |
| Nuvectis Pharma | Fort Lee | NJ | Small Molecules | |
| Nuvig Therapeutics | Redwood City | CA | Novel therapeutics that induce mechanisms of immune homeostasis and treat autoimmune diseases | |
| Oakrum Pharma | St. Louis | MO | Rare Diseases | |
| Obsidian Therapeutics | Cambridge | MA | Cell & Gene Therapies | |
| Obsidio | San Francisco | CA | Bioinspired Material for Minimally Invasive Medical Procedures | |
| Ocelot Bio | San Diego | CA | Peptide therapeutic to treat complications of end-stage liver disease | |
| OCMS Bio | Doylestown | PA | Hybridoma Screening | |
| Octant Biotech | Emeryville | CA | Small Molecules | |
| Octave Bioscience | Menlo Park | CA | Care management platform for neurodegenerative diseases | |
| Ocuphire Pharma | Farmington Hills | MI | Small Molecules for Ophthalmic Indications | |
| Odin Technologies | Chicago | IL | Non-invasive Blood Flow Monitor | |
| Odyssey Therapeutics (2) | Cambridge | MA | Small Molecules, Biologics | |
| Olaregen Therapeutix | New York | NY | Wound Healing | |
| Olive Diagnostics | Menlo Park | CA | Toilet Urinalysis | |
| Olympic Ophthalmics | Issaquah | WA | Tear Encouragement Device | |
| Olympic Protein Technologies | Seattle | WA | Custom Recombinant Proteins | |
| Oncogenuity | New York | NY | Oligonucleotide platform for the treatment of genetically driven cancers | |
| OncoMyx Therapeutics | Phoenix | AZ | Oncolytic Immunotherapy | |
| OnCusp Therapeutics | New York | NY | Small Molecules, ADCs, Bispecifics | |
| OncXerna Therapeutics | Waltham | MA | Cancer Therapeutics | |
| One Codex | San Francisco | CA | Microbiome Sequencing Platform | |
| OneThree Biotech | New York | NY | AI Drug Discovery | |
| ONOCOR | West Chester | PA | atheter-based retrieval system | |
| OnQuality Pharmaceuticals | Seattle | WA | Treatments for cancer side effects | |
| Ontogen Medtech | Lisle | IL | Medical device development services | |
| Optimvia | Cincinnati | OH | Synthetic Heparin | |
| Orcosa | Ewing | NJ | Orally Disintegrating Tablet | |
| Ordinatrix | Phoenix | AZ | Nucleic Acid Programmable Protein Arrays | |
| OrganaBio | South Miami | FL | Modular Cell and Gene Therapy Manufacturing | |
| Organon (2) | Jersey City | NJ | Women’s Health | |
| Origin | Princeton | NJ | Nitric Oxide-emitting Devices | |
| Origin Biosciences | Boston | MA | Synthetic Enzyme | |
| Origin Biosciences | Palo Alto | CA | Synthetic Enzyme | |
| Orna Therapeutics | Cambridge | MA | oRNA, Delivery | |
| Orphan Star Therapeutics | New York | NY | Orphan Drugs | |
| Orphion Therapeutics | New York | NY | Gene Therapy | |
| Oryn Therapeutics | Vacaville | CA | Macrocyclic peptide therapeutics | |
| Otologic Technologies | Madison | UT | Diagnostic AI for Ear Diseases | |
| OTU Medical | San Jose | CA | Consumable endoscopic instruments in urology, pulmonology and other areas | |
| Overture Life | New York | NY | Embryology Lab in a Box | |
| Oviva Therapeutics | New York | NY | Menopause delay through anti-müllerian hormone-like activity | |
| Oyster Point Pharmaceuticals | Princeton | NJ | Ophthalmology Indications | |
| Paige | New York | NY | AI Pathology | |
| Panavance Therapeutics | Berwyn | PA | Small Molecules for Cancer | |
| Pano Therapeutics | San Francisco | CA | Small molecules targeting cellular energetics | |
| Panorama Medicine | Bala Cynwyd | PA | Drug discovery platform for interventions for RNA defects in disease | |
| Panther Orthopedics | Sunnyvale | CA | Superelastic Fixation Device | |
| PanTher Therapeutics | Cambridge | MA | Treatment of inoperable locally advanced solid tumors | |
| PAQ Therapeutics | Cambridge | MA | Restoring health and curing disease through autophagy | |
| Paracrine | San Diego | CA | Regenerative Cell Therapy | |
| Parimer Scientific | Easley | SC | Contract Pharmaceutical Manufacturing | |
| Parse Biosciences | Seattle | WA | Single Cell Sequencing | |
| Parthenon Therapeutics | Cambridge | MA | Cancer Barrier Penetrating Therapies | |
| Partner Therapeutics | Lynnwood | WA | Biologics | |
| Partner Therapeutics | Lexington | MA | Biologics | |
| Pasithea Therapeutics | Miami Beach | FL | ||
| Passage Bio | Philadelphia | PA | Gene Therapy | |
| Pathalys Pharma | Raleigh | NC | CKD Treatments | |
| Perception Neuroscience | New York | NY | Ketamine derivative | |
| Persephone Biosciences | San Diego | CA | Analysis of Poop to Discover Cancer Treatments | |
| Personalized Stem Cells, Inc. | Poway | CA | Stem Cell Processing Services, Patient-funded trials | |
| Phathom Pharmaceuticals | Menlo Park | CA | Novel treatments for gastrointestinal diseases and disorders | |
| Pheast Therapeutics | Palo Alto | CA | Cancer immunotherapy – novel checkpoint therapies | |
| Phenomix Sciences | St. Paul | MN | Genomics and additional ‘omics’ to determine treatment | |
| Phoreus Biotech | Olathe | KS | Branched Amphipathic Peptide Capsules Nanocarriers | |
| Phylex BioSciences | Del Mar | CA | Neutralizing Antibody Discovery | |
| Piccolo Medical | San Francisco | CA | Catheter Navigation Platform | |
| PineTree Therapeutics (2) | Cambridge | MA | Antibody Therapy, Virus-Targeting Recombinant Agent | |
| Pinpoint Science | San Francisco | CA | Bioelectronic Diagnostics | |
| Pinpoint Therapeutics | Philadelphia | PA | Autophagy inhibitors to treat cancer | |
| PionEar Technologies | Boston | MA | Ear Tube Implant | |
| Pipeline Therapeutics | San Diego | CA | Small Molecule for MS | |
| Pleno | San Diego | CA | High-throughput machines for accelerating work in identifying new targets to aid drug development | |
| Plexium | San Diego | CA | Small Molecules Targeting E3 Ligase | |
| Pluristyx | Seattle | WA | Pluristyx, a Seattle-based biotechnology company that helps solve challenges in the field of drug development, regenerative medicine and cell and gene therapy. Pluristyx offers CMC consulting and tech transfer expertise, contract development services, cryopreservation processing, research and clinical-grade Ready-To-Differentiate® Pluripotent Stem Cells. | |
| Pluto Biosciences | Denver | CO | Collaborative Life Sciences Platform | |
| Polares Medical | Palo Alto | CA | Device for mitral valve regurgitation | |
| Polaris Genomics | Rockville | MD | Genomic Biomarker Assay for PTSD | |
| PolyGen Pharmaceuticals | Edgewood | NY | Generics | |
| Ponce Therapeutics | Surfside | FL | Topical Ointment | |
| PostEra | Boston | MA | Machine Learning Medical Chemistry | |
| Precision Diabetes | Cary | NC | Diabetes Diagnostics | |
| Predictus BioSciences | West Roxbury | MA | Molecular Diagnostics | |
| Presto Therapeutics | San Francisco | CA | stem cell based therapeutics for orphan diseases | |
| Pretzel Therapeutics | Waltham | MA | Mitochondrial Therapeutics | |
| Prevail Therapeutics | New York | NY | AAV-based gene therapies | |
| Prime Medicine | Cambridge | MA | Gene Editing Technology | |
| Primmune Therapeutics | Carlsbad | CA | Small Molecules for Oncology | |
| PrinterPrezz | Fremont | CA | 3D-printed Nanotech Spinal Devices | |
| PriZm Therapeutics | Chandler | AZ | Therapies for ultra-rare pediatric orphan diseases | |
| ProBioPharm | Doylestown | PA | Strategy & Business Development Consulting | |
| ProciseDx | San Diego | CA | Diagnostics | |
| ProFound Therapeutics | Cambridge | MA | Protein Target Discovery | |
| PrognomiQ | San Mateo | CA | Multi-omic Diagnostics | |
| ProJenX | New York | NY | Brain-penetrant therapies to address debilitating brain diseases | |
| Prokaryotics | Union | NJ | Antibacterials | |
| PROMISS Diagnostics | Wauwatosa | WI | Ovarian Cancer Diagnostic | |
| Proniras | Seattle | WA | Orphan Neurological Disease Treatments | |
| Proof Diagnostics | Cambridge | MA | POC Covid test | |
| Protabit | Pasadena | CA | Computation Protein Design | |
| Protara Therapeutics | New York | NY | Cell Therapy | |
| Protean BioDiagnostics | Orlando | FL | Oncology Services | |
| Proteovant | King of Prussia | PA | Small Molecule Protein Degraders | |
| Proteowise | New Haven | CT | High-throughput Proteomics | |
| Prothex Pharma | Bridgewater | NJ | Small Molecules | |
| ProTom International | Flower Mound | TX | Proton Therapy | |
| Proxima Clinical Research | Houston | TX | Clinical research | |
| Psilera Bioscience | Tampa | FL | Psychedelics | |
| Psy Therapeutics | Boston | MA | CNS Treatments | |
| PulmoSIM Therapeutics | San Francisco | CA | ||
| Pure Marrow | New Haven | CT | Bone Marrow Stem Cell Harvesting | |
| Pylum Biosciences | South SF | CA | Biologic antibacterials | |
| Pyros Pharmaceuticals | New York | NY | Generics | |
| Pyxis Oncology | Cambridge | MA | Antibody Immunotherapy | |
| Q32 Bio | Cambridge | MA | Biologics to restore healthy immune regulation | |
| QED Therapeutics | San Francisco | CA | Small Molecule Targeting Tyrosine Kinase Receptors | |
| Qlaris Bio | Wellesley | MA | Ocular Small Molecules | |
| Qlarity Imaging | Chicago | IL | Radiology Imaging Software | |
| Qpex Biopharma | San Diego | CA | Anti-infectives | |
| QSAM Biosciences | Austin | TX | Bone-seeking therapeutic radiopharmaceutical | |
| Quanta Therapeutics | South SF | CA | Small Molecules Targeting RAS-driven Cancers | |
| Quench Medical | St. Paul | MN | Respiratory Drug Delivery | |
| Qureator | San Diego | CA | Curiochips designed for recapitulating the complexity of tissue microenvironments, thus providing ideal microscale 3D cell culture conditions | |
| Qx Therapeutics | New Haven | CT | MAP3K2/3 inhibitor | |
| R2M Pharma | South SF | CA | Drug Development Services | |
| Radiance Therapeutics | Emeryville | CA | Ophthalmic Applicator | |
| Radimmune Therapeutics | Burlingame | CA | Molecular targeted radiotherapy | |
| Radionetics Oncology | San Diego | CA | Radiopharmaceuticals | |
| Rain Therapeutics | Newark | CA | Small Molecules | |
| RainBIO | Raleigh | NC | Cornea Gene Therapy | |
| Rallybio | Farmington | CT | Therapeutics | |
| Ranok Therapeutics | Waltham | MA | Innovative targeted protein degradation technology for the discovery and development of novel therapeutics | |
| RapidPulse | Miami | FL | Cyclic Aspiration System for Ischemic Stroke | |
| RareMoon Consulting | Baltimore | MD | US based rare disease regulatory affairs firm focused on EU & US regulations specifically for orphan product development. | |
| Rau Consulting | West Lafayette | IN | ||
| Ravel Biotechnology | San Francisco | CA | Epigenetic Diagnostics | |
| Ray Therapeutics | San Diego | CA | Optogenetic Gene Therapy | |
| RayzeBio | San Diego | CA | Radiopharmaceuticals Therapy for Cancer | |
| ReAlta Life Sciences | Norfolk | VA | Complement and Inflammation Inhibition drug products | |
| Rectify Pharma | Cambridge | MA | Disease-modifying precision therapeutics for patients with serious genetic diseases | |
| Redesign Science | New York | NY | Structure-based Drug Discovery | |
| Redpin Therapeutics | New York | NY | Non-invasive, targeted regulation of neuronal cell activity in the brain by drug activation of cell therapy | |
| ReGelTec | Baltimore | MD | Injectable Hydrogel for Chronic Lower Back Pain | |
| Relavo | Baltimore | MD | Device to prevent infection in peritoneal dialysis | |
| Remedium Bio | Needham | MA | Gene Therapy | |
| Remix Therapeutics | Cambridge | MA | Small molecule therapies designed to reprogram RNA processing | |
| Reneo Pharmaceuticals | San Diego | CA | Genetically-Defined Orphan Therapies | |
| Renerva | Pittsburgh | PA | Implantable technologies to improve the outcome of peripheral nerve repair procedures | |
| Renew Biopharma | San Diego | CA | Cannabinoids | |
| Renibus Therapeutics | Southlake | TX | Small Molecules | |
| Repair Biotechnologies | Syracuse | NY | Cholesterol Therapies | |
| Repertoire Immune Medicines | Cambridge | MA | Cell & Peptide-Based Therapies | |
| Replicate Bioscience | San Diego | CA | Preventing oncology drug resistance | |
| Reprieve Cardiovascular | Milford | MA | Heart Failure Device | |
| Reprise Biomedical | Plymouth | MN | Biological medical devices manufactured using a proprietary perfusion decellularization technology that supports cellular integration. | |
| Resilience | East Norriton | PA | Biomanufacturing | |
| Resilience | Marlborough | MA | Biomanufacturing | |
| Resilience | Durham | NC | Biomanufacturing | |
| Resilience | Alameda | CA | Biomanufacturing | |
| Resilience | Alachua | FL | Biomanufacturing | |
| Resilience | Waltham | MA | Biomanufacturing | |
| Resilience | La Jolla | CA | Biomanufacturing | |
| Resilience | Allston | MA | Biomanufacturing | |
| Respira Labs | Mountain View | CA | Wearable Lung Monitor | |
| Respirix | San Francisco | CA | Cardiac Monitoring | |
| Respirogen | Boulder | CO | Stabilizing and delivering oxygen for targeted clinical indications | |
| ResVita Bio | Berkeley | CA | Engineered Skin Probiotics | |
| Retro Biosciences | Redwood City | CA | Cell reprogramming | |
| Revel Pharmaceuticals | San Francisco | CA | Therapeutic Enzymes | |
| Revelation Biosciences | Menlo Park | CA | Immunologic Therapeutics & Diagnostics | |
| Reverie Labs | Cambridge | MA | Brain-penetrant cancer therapies | |
| ReviR Therapeutics | San Francisco | CA | Building a Scalable Platform addressing unmet therapeutic needs by REVIsing RNA with Small Molecules | |
| ReviveMed | Cambridge | MA | AI-Driven Drug Discovery using Metabolomics | |
| Rgenta Therapeutics | Woburn | MA | RNA-targeting medicines | |
| Rhaeos | Evanston | IL | Shunt Monitor | |
| Ridgeline Therapeutics | Houston | TX | Small Molecules | |
| Ring Therapeutics | Cambridge | MA | Gene Therapy Targeting the Human Commensal Virome | |
| RION | Rochester | MN | Exosome Therapeutics | |
| Rise Therapeutics | Rockville | MD | Orally Bioavailable Protein Therapeutics | |
| Rizana Therapeutics | Quincy | MA | Treatments for Drug Addiction | |
| RLS Therapeutics | Nashville | TN | Small Molecule | |
| RogCon Biosciences | San Diego | CA | Antisense Oligo | |
| ROME Therapeutics | Cambridge | MA | Drugging Junk DNA | |
| Ronawk | Olathe | KS | Stem Cell Growth Technology | |
| Rondo Therapeutics | Menlo Park | CA | Immuno-oncology platform for treating solid tumors, Bispecific Antibodies | |
| RootPath Genomics | Watertown | MA | Personalized T Cell Therapy Platform | |
| RosVivo Therapeutics | Reno | NV | miRNA & siRNA Therapies | |
| Rubedo Life Sciences | Sunnyvale | CA | Age-related drug discovery platform | |
| Rubik Therapeutics | Cambridge | MA | Cell Therapies for Solid Tumors | |
| RubrYc Therapeutics | San Carlos | CA | Antibody Therapeutics | |
| Rumi Scientific | New York | NY | Organoid-like diagnostic platform | |
| Rune Labs | San Francisco | CA | Brain data analysis platform | |
| RVAC Medicines | Medford | MA | mRNA, vaccines, and lipid nanoparticle technologies | |
| SalioGen Therapeutics | Burlington | MA | Gene Therapy Platform Technology | |
| Sampled | Piscataway | NJ | Biologics Services & Research | |
| Samsara Therapeutics | Virtual | MA | Small Molecules | |
| Sana Biotechnology | Seattle | WA | Cell & Gene Therapies | |
| Sandhill Therapeutics | Dallas | TX | CAR-T Technology | |
| Scintillant Bioscience | Salt Lake City | UT | Drug Discovery Services | |
| Scioto Biosciences | Indianapolis | IN | Delivery of microbiome therapeutics | |
| Scitara | Marlborough | MA | Digital Connectivity for Labs | |
| Scopus BioPharma | New York | NY | Immuno-oncology Gene Therapy | |
| Scorpion Biological Services | San Antonio | TX | Contract Large Molecule Manufacturing | |
| Scorpion Therapeutics | Boston | MA | Small Molecules | |
| Seascape Clinical | Redwood City | CA | Clinical Operations Cloud Software | |
| Secura Bio | Las Vegas | NV | Acquisition & Worldwide Commercialization | |
| Seer | Redwood City | CA | Early Detection | |
| Segmed | Menlo Park | CA | Cloud based platform for AI development | |
| Seismic Therapeutics | Watertown | MA | Bispecific therapeutic antibodies | |
| Selkirk Pharma | Spokane | WA | Contract Manufacturing – Pharma | |
| Selva Therapeutics | Del Mar | CA | ||
| Sema4 Genomics | Stamford | CT | Genetic Data | |
| Seneca Therapeutics | Blue Bell | PA | Oncolytic immunotherapeutic | |
| Septerna | South SF | CA | GPCR Drug Discovery | |
| SeromYx Systems | Cambridge | MA | Systems Serology | |
| SG Devices | St. Paul | MN | Optimized Augmented Reality in the Cardiac Catheterization Laboratory | |
| Shape Therapeutics | Seattle | WA | RNA-editing gene therapy | |
| Sherlock Biosciences | Boston | MA | Molecular Diagnostics | |
| Shoreline Biosciences | San Diego | CA | Cell-Based Immunotherapies | |
| ShouTi | South SF | CA | Small Molecules | |
| Sidereal Therapeutics | Boston | MA | First-in-class treatments for Acute Kidney Injury & Iron-Mediated Disorders | |
| Siduma Therapeutics | New Haven | CT | Heterobifunctional molecule | |
| Signet Therapeutics | Boston | Cancer Therapies | ||
| Sigyn Therapeutics | San Diego | CA | Blood Purification Technology | |
| SimBioSys | Champaign | IL | Tumor Analysis Software | |
| SimBioSys | Chicago | IL | Tumor Analysis Software | |
| SinuSonic | Columbia | SC | Nasal Congestion Relief Device | |
| Siolta Therapeutics | San Carlos | CA | Gut Microbiome Modification | |
| Sionna Therapeutics | Natick | MA | Small Molecule Targeting CF | |
| Skyhawk Therapeutics | Waltham | MA | RNA-correcting Small Molecules | |
| Skyline Biosciences | Chicago | IL | Oncology | |
| Skyran Biologics | Hershey | PA | Ophthalmological Small Molecule | |
| Sling Therapeutics | Ann Arbor | MI | Oral Small Molecule for Thyroid Eye Disease | |
| SmartPharm Therapeutics | Cambridge | MA | Production of biologics within patients via gene therapy | |
| Socium Therapeutics | Parsippany | NJ | Orally administered immunotherapy platform based on recombinant Salmonella typhi | |
| Solarea Bio | Cambridge | MA | Microbiome Treatments | |
| Sollis Therapeutics | Columbus | OH | Non-steroidal, Non-opioid analgesics | |
| Sonoma Biotherapeutics | South SF | CA | Cell Therapy | |
| Sorriso Pharmaceuticals | Salt Lake City | |||
| South Rampart Pharma | New Orleans | LA | Non-opioid Pain & Fever Treatments | |
| Souvie Biodelivery | Tucson | AZ | Drug Delivery Development | |
| Sparx Therapeutics | Mount Prospect | IL | Antibodies, CAR-T, ADC | |
| SpectraWAVE | Bedford | MA | Medical Imaging Platform | |
| SPES Pharmaceuticals | North Brunswick | NJ | 505 b(2) Small Molecules | |
| Spesana | Memphis | TN | Clinical Decision Software | |
| SpinTech MRI | Birmingham Farms | MI | MRI Diagnosis Software | |
| SpIntellx | Pittsburgh | PA | Image Analysis | |
| Spirita Oncology | Natick | MA | Small Molecule for Cancer | |
| Spotlight Therapeutics | Hayward | CA | In vivo Gene Editing | |
| Spriggs Bioanalytical Consulting | Lenexa | KS | Consulting specializing in the bioanalytical aspects of biopharmaceutical product development from early exploratory studies to post marketing | |
| Spring Discovery | Palo Alto | CA | AI for Aging Therapies | |
| SpringWorks Therapeutics | Durham | NC | Small Molecules | |
| SpringWorks Therapeutics | Stamford | CT | Small Molecules | |
| Starlight Cardiovascular | San Diego | CA | Devices for Congenital Heart Defects | |
| Starton Therapeutics | Paramus | NJ | Transdermal Delivery Technology, 505(b)(2) | |
| STAT3 Therapeutics | Coral Springs | FL | Drugs Targeting STAT3 | |
| Statera Therapeutics | New Haven | CT | Nanoparticle Therapies | |
| Stelexis Therapeutics | Bronx | NY | Drugs targeting pre-cancerous stem cells | |
| StemCellerant | Cambridge | MA | Stem Cell Contract Research & Services, Stem Cell Therapy | |
| Stemson Therapeutics | San Diego | CA | iPSC Hair Loss Treatment | |
| Stingray Therapeutics | Houston | TX | Small Molecule | |
| Strand Therapeutics | Cambridge | MA | Gene Therapy | |
| Strategikon Pharma | San Francisco | CA | Clinical Maestro by Strategikon. Digital tools for the business side of clinical trials. | |
| Strateos | Menlo Park | CA | Robotic Cloud Lab | |
| StrideBio | Durham | NC | Antibody-Evading Gene Therapy | |
| STRM.BIO | Boston | MA | Extracellular vesicles (EVs) to deliver gene therapies | |
| Styx Biotechnologies | San Diego | CA | Vaccines | |
| Sublimity Therapeutics | Solana Beach | CA | Small Molecule | |
| SummerBio | Menlo Park | CA | High-throughput Diagnostics Platform | |
| Sunflower Therapeutics | Hingham | MA | Efficient biologics drug development platform | |
| Supira Medical | Los Gatos | CA | Low-profile, high-flow percutaneous ventricular assist device | |
| Surf Bio | Palo Alto | CA | Biologic Stabilization Platform | |
| Surface Ophthalmics | Pleasanton | CA | 505(b)(2) drugs | |
| SwanBio Therapeutics | Bala Cynwyd | PA | Gene Therapy | |
| Syncromune | Fort Lauderdale | FL | Intratumoral Immunotherapy | |
| Synspira Therapeutics | Framingham | MA | Inhaled glycopolymer-based therapeutics for the treatment of pulmonary disease | |
| Synthekine | Menlo Park | CA | Engineered Cytokines | |
| Tactiva Therapeutics | Buffalo | NY | Adoptive Cell Therapy | |
| TAE Life Sciences | Foothill Ranch | CA | Boron Neutron Capture Therapy | |
| Tailored Therapeutics | Germantown | MD | Personalized Immune Therapy | |
| Tallac Therapeutics | Burlingame | CA | Novel Cancer Immunotherapies | |
| Tamuro Bio | Wayne | PA | NASH Treatment | |
| Tarsus Pharmaceuticals | Irvine | CA | Blepharitis Treatment | |
| Tarus Therapeutics | New York | NY | Lead programs target the immunosuppressive adenosine pathway in the tumor microenvironment (TME) for the treatment of resistant cancers | |
| Tavros Therapeutics | Durham | NC | Small Molecule Cancer Therapy | |
| Taysha Gene Therapies | Dallas | TX | Adeno-associated virus gene therapies | |
| Tectonic Therapeutic | Watertown | MA | GPCR Targeting Drugs | |
| Tegmine Therapeutics | South SF | CA | Antibody Drug Discovery Platform | |
| TellBio | Beverly | MA | Liquid Biopsy Platform | |
| Tellus Therapeutics | Durham | NC | Treatment for Neonatal Brain Injury | |
| Ten63 Therapeutics | Durham | NC | Computational chemistry and mathematically guaranteed, superlinear search algorithms to find optimized drug candidates | |
| TendoNova | Atlanta | GA | Ultrasound-guided orthopedic procedures | |
| TenSixteenBio | San Francisco | CA | Somatic mosaicism and clonal hematopoiesis of indeterminate potential (CHIP) to discover and develop novel therapeutics | |
| Tentarix Biotherapeutics | San Diego | CA | Logic-Gated Multivalent Molecules | |
| Teon Therapeutics | Redwood City | CA | Small molecules focused on GPCR targets for oncology indications | |
| Teres Bio | Oakland | CA | Dermatological Topical | |
| Terns Pharmaceuticals | Foster City | CA | Small Molecules – Liver focus | |
| Terray Therapeutics | Pasadena | CA | Spatially encoded screening and optimization platform | |
| Tessera Therapeutics | Cambridge | MA | Gene Writing | |
| Tevard Biosciences | Cambridge | MA | tRNA-based Gene Therapies | |
| Tevogen Bio | ZZ | NJ | T Cell Therapy for Covid | |
| TFF Pharmaceuticals | Fort Worth | TX | Dry-powder Inhalation for Respiratory Therapies | |
| The Cytokine Core | Indianapolis | IN | Cytokine Analysis | |
| Theradaptive | Frederick | MD | Protein-engineering Technology | |
| Theseus Pharmaceuticals | Cambridge | MA | Kinase Inhibitors | |
| Thymmune Therapeutics | Cambridge | MA | Thymic engineering platform and cell therapies | |
| Timber Pharmaceuticals | Basking Ridge | NJ | Dermatological Conditions | |
| Ting Therapeutics | Omaha | NE | Hearing Loss Treatments | |
| Tioga Medical | Campbell | CA | Valve Replacement | |
| Titan Clinical Solutions | Phoenix | AZ | Hyperbaric & wound Care Clinical Trials | |
| Toralgen | Indianapolis | IN | Nanoparticle Formulations | |
| Torus Biosystems | Cambridge | MA | Diagnostics | |
| Totus Medicines | Emeryville | CA | Covalent Small Molecules | |
| Trace Orthopedics | Philadelphia | PA | Minimally-invasive Tendon Surgery | |
| Tradewind Bioscience | Daly City | CA | Antibody Therapy | |
| Transition Bio | Cambridge | MA | Condensate technology, liquid-liquid phase separation | |
| Travecta Therapeutics | New York | NY | Brain Drugs | |
| Treadwell Therapeutics | New York | NY | Oncology Small Molecules | |
| Treeline Biosciences | Watertown | MA | Molecular targets in oncology that are validated but difficult to drug | |
| Tregeutix | Orlando | FL | Antigen-specific immunotherapeutic approaches | |
| TregTherapeutics | Chapel Hill | NC | Tolerogenic vaccine | |
| Tremeau Pharmaceuticals | Concord | MA | Non-opioid pain therapies | |
| Treovir | Philadelphia | PA | Oncolytic HSV immunotherapy | |
| TRexBio | South SF | CA | Treg mapping in human tissues | |
| Triad Life Sciences | Memphis | TN | Extracellular Matrix | |
| TriAltus Bioscience | Birmingham | AL | Protein Purification Products & Services | |
| Triana Biomedicines | Waltham | MA | Platform to discover and develop molecular glues – E3 ubiquitin ligases | |
| Trident Bioscience | Mountain View | CA | Custom Protein Development | |
| Trilo Therapeutics | San Francisco | CA | PPI inhibitors | |
| Trishula Therapeutics | South SF | CA | Cancer Immunotherapy | |
| Trutino Biosciences | San Diego | CA | Locally activated cytokine precursors | |
| Truvic Medical | Campbell | CA | Thrombus Removal | |
| TScan Therapeutics | Waltham | MA | T Cell Therapies | |
| Tune Therapeutics | Durham | NC | Epi-therapeutic Medicines | |
| Turn Biotechnologies | Mountain View | CA | mRNA Therapies | |
| Tvardi Therapeutics | Houston | TX | STAT3 inhibitors | |
| Tyra Biosciences | Carlsbad | CA | Purpose-built cancer drugs | |
| Ultima Genomics | Newark | CA | High-throughput, low-cost sequencing platform | |
| Umoja Biopharma | Seattle | WA | Cellular immunotherapy platform | |
| Uncommon Innovation | Philadelphia | PA | Medical Device Design & Regulatory Consulting | |
| Unicus Pharmaceuticals | Taunton | MA | Contract R&D services; Topical and Oral Semisolids, Solutions & Suspensions; Drug Delivery | |
| Unlearn | San Francisco | CA | Machine-learning technology that creates digital twins of patients in clinical trials | |
| Unnatural Products | Santa Cruz | CA | Macrocylic Peptides plus AI | |
| Upstream Bio | Waltham | MA | Therapies for allergic, inflammatory conditions | |
| URO-1 | Winston-Salem | NC | Prostate biopsy for men and treatment for overactive bladder (OAB) in women | |
| Urovant Sciences | Irvine | CA | Small Molecule, Gene Therapy | |
| Uvax Bio | Wilmington | DE | Single-component self-assembling protein nanoparticle vaccine | |
| Valence Discovery | Cambridge | MA | AI-Enabled Drug Design | |
| Valo Health | Branford | CT | Drug Discovery & Development Engine | |
| Valo Health | Princeton | NJ | Drug Discovery & Development Engine | |
| Valo Health | San Francisco | CA | Drug Discovery & Development Engine | |
| Valo Health | Lexington | MA | Drug Discovery & Development Engine | |
| Vanqua Bio | Chicago | IL | Small Molecules Targeting Neuro Indications | |
| Vascugen | Madison | WI | Regenerative Therapies | |
| VasoRx | Santa Barbara | CA | RNA delivery | |
| Vast Therapeutics | Durham | NC | Nitric Oxide | |
| VastBiome | Millbrae | CA | Unlocking the power of the human gut microbiome | |
| Vektor Medical | San Diego | CA | Technology designed for functionally mapping cardiac arrhythmias | |
| Velocity Clinical Research | Durham | NC | Clinical Research Organization | |
| Veloxity Labs | Peoria | IL | Veloxity Labs, LLC is a premier bioanalytical CRO focused on LC-MS bioanalysis. Our unique structure and systems deliver on our promise of operating at 80% capacity to expedite timelines to our sponsors. | |
| VenoStent | Houston | TX | External vein stent | |
| VenoStent | Dallas | TX | External vein stent | |
| VenoStent | Boston | MA | External vein stent | |
| VenoStent | Nashville | TN | External vein stent | |
| Venquis Therapeutics | San Diego | CA | Protein Degradation Small Molecules | |
| Ventus Therapeutics | Waltham | MA | Small Molecules targeting proteins in the inflammasome and nucleic acid sensing signaling pathways | |
| Ventyx Biosciences | Encinitas | CA | Therapeutics targeting innate and adaptive immune systems | |
| Vera Therapeutics | South SF | CA | Gene Editing Technology | |
| Veralox Therapeutics | Frederick | MD | Therapeutics Targeting 12-Lipoxygenase | |
| Veravas | Oakdale | MN | Diagnostics | |
| VeriSIM Life | San Francisco | CA | Biosimulations | |
| Verismo Therapeutics | Philadelphia | PA | Cell Therapy | |
| Verix Health | Santa Clara | CA | Surgical Device Platform | |
| Vernal Biosciences | Colchester | VT | mRNA Production | |
| Verogen | San Diego | CA | Forensic Sequencing | |
| Verra Therapeutics | Ithaca | NY | Biologics, Small Molecule | |
| Versanis Bio | Oakland | CA | ||
| VersaPeutics | San Diego | CA | Nervous System Disorder Treatments | |
| Versatope Therapeutics | Lowell | MA | Exosomes derived from probiotics | |
| Verseau Therapeutics | Bedford | MA | Macrophage checkpoint modulators, Monoclonals Antibodies | |
| Verve Therapeutics | Cambridge | MA | Gene-editing Treatments | |
| Vesalius Therapeutics | Cambridge | MA | ||
| Vesigen Therapeutics | Cambridge | MA | Fusogenic extracellular vesicle delivery technology | |
| Vibliome | New York | NY | Small Molecule Kinase Inhibitors | |
| Vibliome | Bozeman | MT | Small Molecule Kinase Inhibitors | |
| Videra Surgical | San Francisco | CA | Breast Marker for Orientation during cancer intervention | |
| Vigil Neuroscience | Cambridge | MA | Microglia-based Therapeutics for Neurodegenerative Diseases | |
| Vincere Biosciences | Cambridge | MA | Small Molecules to Target Parkinson’s | |
| Vincerx Pharma | Palo Alto | CA | Small Molecules | |
| Vineti | San Francisco | CA | Cloud-based cell-therapy management system | |
| Viscient Biosciences | San Diego | CA | 3D tissue technology to discover and develop drugs | |
| Viseon | Irvine | CA | Minimally Invasive Spine Surgery | |
| Visible Genomics | Oakbrook Terrace | IL | AMD Diagnostic | |
| Visiox Pharma | Tarrytown | NY | Ophthalmology Treatments | |
| Vistara Bioscience | Woodbridge | CT | Drug Discovery Platform | |
| Visus Therapeutics | Irvine | CA | Presbyopia-correcting eye drops | |
| Visus Therapeutics | Seattle | WA | Presbyopia-correcting eye drops | |
| VITRAC Therapeutics | Boston | MA | ||
| VitriVax | Boulder | CO | Thermostabilization and Atomic Layer Deposition methods for Vaccine Formulation | |
| ViTToria Biotherapeutics | Philadelphia | PA | T Cell Therapies | |
| Vivasc Therapeutics | Pittsburgh | PA | Cardiac Targeting Peptide platform technology | |
| Vivera Pharmaceuticals | Newport Beach | CA | Opioid deterrence and cessation and non-addictive solutions for pain management | |
| Vivid Genomics | San Diego | CA | Genomic Biopsies | |
| Vivid Microscopy | Wauwatosa | WI | Imaging | |
| Vivtex | Cambridge | MA | Oral Biologic Delivery | |
| Vizgen | Cambridge | MA | Next-generation spatially resolved, single-cell transcriptomics | |
| Volastra Therapeutics | New York | NY | Therapies for the treatment of metastatic cancers | |
| Volta Labs | Cambridge | MA | Genomic Sample Prep Technology | |
| Vuja De Sciences | Natick | MA | Targeting the unique vulnerability of undetected disseminated tumor cells before they can cause deadly metastatic recurrence | |
| Vyant Bio | Cherry Hill | NJ | Functional microtissues engineered from induced pluripotent stem cells to facilitate high-throughput, human-based drug discovery | |
| Walden Biosciences | Cambridge | MA | Podocyte-targeting Kidney Disease Treatments | |
| Walking Fish Therapeutics | South SF | CA | Cell-Based Protein Factories to Treat Serious Disorders | |
| Weatherwax | San Francisco | CA | Next-gen bifunctional small molecule drug discovery | |
| Werewolf Therapeutics | Cambridge | MA | Cancer Treatments | |
| Wesana Health | Chicago | IL | Psychedelic Therapies | |
| Wheeler Bio | Oklahoma City | OK | Biomanufacturing | |
| WojTek Mechanical Design Engineering & Machine | Oerman | MO | Medical & BioMedical, R&D, Automating Processes with the newest technology, and Tooling Design. | |
| Woolsey Pharmaceuticals | New York | NY | 505(b)(2) for Neurodegenerative | |
| Wugen | St. Louis | MO | Off-the-shelf Cell Therapies for Cancer | |
| WuXi Diagnostics | Rochester | MN | Diagnostic Platform | |
| X-37 | South SF | CA | AI Drug Discovery | |
| X-Cor Therapeutics | Boston | MA | Extracorporeal CO2 removal device | |
| xCures | Oakland | CA | AI-based precision oncology clinical study platform | |
| Xentria | Chicago | IL | Biologics & Biosimilars | |
| Xilio Therapeutics | Waltham | MA | Cancer Immunotherapies | |
| Xilis | Durham | NC | Micro-organosphere technologies to guide precision therapy for cancer patients | |
| XinThera | San Diego | CA | Small molecules – oncology and immunology | |
| xMD Diagnostics | Baltimore | MD | Molecular Diagnostics | |
| Xyphos | South SF | CA | Cell-based cancer therapies | |
| YourChoice Therapeutics | Berkeley | CA | Birth Control | |
| YouthBio Therapeutics | Seattle | WA | Gene therapies aimed at restoring more youthful epigenetic profiles with the help of partial reprogramming | |
| ZabBio | San Diego | CA | Monoclonal Antibodies | |
| Zentalis Pharmaceuticals | San Diego | CA | Small Molecules | |
| Zephyr AI | Tysons Corner | VA | AI Data Analysis | |
| Zeta Surgical | Boston | MA | Surgical Guidance Technology | |
| ZimVie | Parsippany | NJ | Dental & Spinal Implants; Allografts | |
| ZimVie | Palm Beach Gardens | FL | Dental & Spinal Implants; Allografts | |
| ZimVie | Westminster | CO | Dental & Spinal Implants; Allografts | |
| Zionexa | Fishers | IN | In-vivo biomarkers to guide targeted therapies in oncology | |
| ZKR Orthopedics | San Francisco | CA | Knee Replacement | |
| Zylo Therapeutics | Greenville | SC | Drug Delivery | |
| Adolore Biotherapeutics | Delray Beach | FL | Gene Therapy Analgesic for Pain | |
| Aethon Therapeutics | New York | NY | Antibody immunotherapies for tumors that have developed resistance | |
| ApiJect | Stamford | CT | Single-use injectable delivery system | |
| Arugula Sciences | Irving | TX | Umbilical Cord Allograft | |
| AssayQuant | Marlborough | MA | Fluorescence Microplate Assays | |
| Atomic AI | South SF | CA | AI-based RNA Drug Discovery | |
| Avema Pharma Solutions | Westbury | NY | CDMO | |
| AVS Pulse | Ann Arbor | MI | Treating severely calcified arterial disease | |
| Bio4t2 | San Diego | CA | CAR-T Cell Therapies | |
| BioCorRx | Anaheim | CA | Addiction Treatments | |
| BioSpectra | Bangor | CA | GMP-grade ingredients and reagents | |
| Cadrenal Therapeutics | Ponte Vedra | FL | Orphan-designated novel cardiorenal therapeutic | |
| Cell BioEngines | Boston | MA | Cell-based Immunotherapies | |
| Cyrano Therapeutics | Delray Beach | FL | Treatment to restore sense of smell | |
| CytoAgents | Pittsburgh | PA | NF-kB targeting therapy | |
| EndoTheia | Nashville | TN | Next-generation devices for flexible endoscopy | |
| Equilibre Biopharmaceuticals | New York | NY | Neurological Therapies | |
| Excite Pharma Services | Lee’s Summit | MO | Analytical chemistry services, cGMP manufacturing and sterile fill services | |
| ExeGi Pharma | Rockville | MD | Live Therapeutics | |
| G3 Therapeutics | Midlothian | VA | Drug Discovery Platform | |
| Gensaic | Cambridge | MA | Phage-derived Particles for Gene Delivery | |
| H&A Scientific | Greenville | NC | LIMS, Stability Software | |
| Hap10 Bio | San Francisco | CA | Treating resistance to covalent inhibitors of oncoproteins | |
| Iaso Therapeutics | East Lansing | MI | Vaccines | |
| Illuminare Biotechnologies | Brooklyn | NY | Nerve Imaging | |
| Immunyx Pharma | New York | NY | Neutrophil-Modulation Therapy | |
| Infinity Neuro | Lake Forest | CA | Device to treat stroke | |
| Interbiome | Rockville | MD | Drug CMO | |
| Isterian Biotech | Boston | MA | Small molecule inhibitors of transglutaminase 2 | |
| Kanpecia | Lawrence | KS | Alopecia Treatment | |
| Kimia Therapeutics | Berkeley | CA | Treatment for metabolic disease | |
| LAPIX Therapeutics | Boston | MA | On-Off Immunity Treatments | |
| Lighthouse Pharmaceuticals | San Francisco | MA | Small molecule protease inhibitors | |
| Love Lifesciences | Overland Park | KS | Single use hybrid injection device | |
| MedTherapy Biotechnology | Wuincy | MA | Cell, Gene & Immunotherapies for Cancer | |
| Neochromosome | Long Island City | NY | DNA Services | |
| Nexalin Technology | Houston | TX | Neuromodulation Device | |
| NextPoint Therapeutics | Cambridge | MA | Antibody Therapies | |
| Oculogenex | La Habra | CA | Gene Therapy for Vision | |
| OcuSciences | Ann Arbor | MI | Ocular Imagers | |
| OncoBay Clinical | Raleigh | NC | Boutique Oncology Clinical Research Organization | |
| Oncotelic Therapeutics | Agoura Hills | CA | transforming growth factor beta 2 inhibitor | |
| Pepper Bio | Boston | MA | Transomics drug discovery | |
| Prapela | Biddeford | ME | neonatal Respiratory Therapy | |
| Precision Neuroscience | New York | NY | Brain–computer interface implants | |
| Primera Therapeutics | Rockville | MD | mtDNA engineering toolbox for mitochondrial diseases | |
| Regel Therapeutics | Cambridge | MA | AAV gene delivery | |
| restor3d | Durham | NC | 3D printed implants and devices | |
| SanegeneBio | Woburn | MA | siRNA Drug Discovery | |
| Seragon Biosciences | Irvine | CA | AI Vaccine Design | |
| SynerFuse | Eden Prairie | MN | Spinal fusion and neuromodulation concept | |
| Tempero Bio | Oakland | CA | Treatments for substance abuse disorders | |
| Vector BioMed | Gaithersburg | MD | Gene and cell therapy production | |
| Velsera | Charlestown | MA | Biomedical data analysis platform | |
| Vici Health Sciences | Elkridge | MD | CDMO providing formulation development, regulatory services, and analytical testing | |
| Visura Technologies | Bloomington | MN | Disposable camera that seamlessly connects to a transesophageal echocardiogram probe | |
| Eyedea Medical | Baltimore | MD | Corneal Transplantation | |
| Hanimune Therapeutics | Philadelphia | PA | Food allergy treatment | |
| Transcend Therapeutics | New York | NY | Psychedelics | |
| Transmural Systems | Andover | MA | Electrosurgical transcatheter guidewire system | |
| Aera Therapeutics | Boston | MA | Genetic Medicines | |
| Alveolus Bio | Birmingham | AL | Commensal bacteria as lung therapy | |
| Austin Biosciences | Austin | MN | Cancer Diagnostics | |
| Biolase | Foothill Ranch | CA | Dental Lasers | |
| CorePharma | Middlesex | NJ | Generics | |
| Expanding Innovations | Mountain View | CA | Non-screw based expandable cage technology | |
| HBM Alpha Therapeutics | Cambridge | MA | Antibody Therapeutics | |
| Morphoceuticals | Oklahoma City | OK | Ion-channel drug with localized bioreactors | |
| MuriGenics | Vallejo | CA | In-vivo and in-vitro contract drug discovery and development services | |
| Nanite | Boston | MA | AI-driven polymer design platform focused on next-generation, non-viral gene delivery | |
| Novelstar Pharmaceuticals | Cranbury | NJ | 505(b)(2) | |
| OFD Biopharma | Albany | OR | Lyophilization | |
| Psivant | Boston | MA | Physics-driven Drug Design | |
| Purolite Chromatography Services | King of Prussia | PA | Ion-exchange Resin | |
| Ryne Biotechnology | San Diego | CA | iPSC dopamine progenitor | |
| Sentia Medical Sciences | San Diego | CA | Novel peptide therapeutics | |
| Sword Bio | Carmel | IN | Large molecule assay development, validation and sample testing for PK, Biomarkers, Immunogenicity and Nab assays | |
| veranova | Wayne | PA | CDMO – APIs, Biologics | |
| VST Bio | San Diego | CA | Antibodies that target novel pathways | |
| Wilmington PharmaTech | Newark | DE | Integrated CRO/CMO Clinical Drug Development Services | |
| Allosteric Bioscience | New York | NY | Treatments for aging | |
| Aracari Biosciences | Irvine | CA | Vascularized Tissues that mimic the Human Body | |
| Biojo Sciences | Bethesda | MD | Drugs | |
| BioTheraVision | Chicago | IL | 505(b)(2) for Ophthalmology | |
| BLA Regulatory | Gaithersburg | MD | Providing end-to-end tailored regulatory strategy and execution services from INDs to NDA/BLAs | |
| Breakthrough Pharma | Morgantown | WV | Pharmaceutical Consulting | |
| Capzer Pharmaceuticals | Lake Worth | FL | GC, HPLC Services | |
| Cell Mosaic | Woburn | MA | Bioconjugation Tools | |
| CG Scientific | Worcester | MA | Cell Manufacturing Automation Solutions | |
| CMO partners | Billerica | MA | Contract development and manufacturing | |
| Curio Bioscience | Palo Alto | CA | High Resolution Spatial Biology | |
| Dimension Inx | Chicago | IL | 3D printed grafts, ceramics | |
| EliteImmune | Gaithersburg | MD | Customized reagents and services for monoclonal antibody develeopment | |
| Elixell Therapeutics | Kansas City | KS | Stem Cell Therapy | |
| Engineered BioPharmaceuticals | Danville | VA | Formulation, Analytical, Contract Manufacturing | |
| EpiBiologics | San Mateo | CA | Bispecific Antibody | |
| GQ Life Sciences | Alpharetta | GA | Gene Patent Query Software | |
| Halda Therapeutics | New Haven | CT | Regulated Induced Proximity TArgeting Chimeras | |
| InnDura Therapeutics | Cambridge | MA | Next-Generation Paradigm for Armed Memory-Like Innate Immune Cell Therapies | |
| Innovo Bioanalysis | Mansfield | MA | Analytical Services | |
| Kano Therapeutics | Cambridge | MA | Design and engineering of novel genetic vectors | |
| Lirum Therapeutics | New York | NY | Biologic-Small Molecule Conjugate | |
| Osteal Therapeutics | Dallas | TX | Drug-device combination for joint infection prevention | |
| Ostial Corporation | Campbell | CA | Dual-ballooon Stent | |
| Proteologix | Redwood City | CA | Antibodies provider | |
| Ronawk | Olathe | KS | Cell-growth scaffold blocks | |
| Conagen | Bedford | MA | Microbial Production | |
| Piezo Therapeutics | Atlanta | GA | Nucleic Acid Drug Delivery | |
| Qvin | Menlo Park | CA | menstrual Blood Analysis | |
| Red Queen Therapeutics | San Diego | CA | Fusion inhibitors to prevent and treat viral infections | |
| Slate Bio | Charlottesville | VA | Treg therapy for autoimmune diseases | |
| Speid Associates | San Diego | CA | Training in new medicine development | |
| TransMed7 | Phoenix | AZ | Access Devices | |
| Via Scientific | Cambridge | MA | Multi-omics Platform | |
| Advamedica | Cambridge | MA | Biomaterial based medical devices for pre-hospital, intra-operative and post-operative clinical needs | |
| ADvantage Therapeutics | Miami | FL | Alzheimer’s Treatments | |
| Aldena Therapeutics | Boston | MA | siRNA-based therapies for dermatological therapies | |
| Ampersand Biomedicines | Cambridge | MA | Programmable medicines | |
| Artera | Los Altos | CA | AI Diagnostics | |
| Asylia Therapeutics | Houston | TX | Antibody Therapy | |
| AuraVax Therapeutics | Philadelphia | PA | Intranasal Delivery | |
| AusperBio | San Mateo | CA | Pan-genotypic antisense oligonucleotide targeting all HBV RNA | |
| Caira Surgical | New York | NY | Radar surgical tracking for navigated and robotic joint replacement surgery | |
| CancerVax (2) | Santa Barbara | CA | Immuno-oncology | |
| Cardio Diagnostics | Chicago | IL | Cardiovascular Diagnostics | |
| CARGO Therapeutics | San Mateo | CA | CAR T Cell Therapy | |
| Cellsonics | San Jose | CA | Single Cell Sample Prep | |
| Certis Oncology Solutions | San Diego | CA | Cancer therapy recommendation platform, preclinical CRO | |
| Cloudbyz | Naperville | IL | Clinical Trial Management Software | |
| Cosmo Bio | Carlsbad | CA | Lab Reagents | |
| Covant Therapeutics | Boston | MA | Covalent small molecules targeting post-translational modification sites | |
| Culmination Bio | Saint George | UT | Anonymized, and de-identified intelligence platform | |
| Droplet Biosciences | Cambridge | MA | Non-invasive liquid lymph biopsy | |
| Ebvia | San Francisco | CA | Covid Treatment | |
| Endogenex | Plymouth | MN | Specialized catheter that delivers pulsed electric fields to the duodenum | |
| Evanoa Bioscience | Alachua | FL | Cell line production of recombinant proteins, viral vaccines, gene therapies and plasmids | |
| Evergreen Theragnostics | Springfield | NJ | CSMO, Radiochemistry, Clinical & Commercial Manufacturing | |
| FemDx Medsystems | Santa Clara | CA | Falloposcope | |
| INTEGRA Biosciences | Hudson | NH | Liquid Handling, Pipettes | |
| International Process Solutions | San Carlos | CA | Calibration, validation, preventative maintenance, and data management services | |
| Life Magnetics | Ann Arbor | MI | Carbon-based RNA isolation kits and services | |
| Mercury Bio | Santa Fe | NM | Next-generation Biomolecular Drug Delivery Platform | |
| Mozarc Medical | Minneapolis | MN | Scaling Dialysis Delivery | |
| MS Bioworks | Ann Arbor | MI | Protein mass spectrometry contract research | |
| Myosin Therapeutics | Jupiter | FL | Novel medications targeting cellular motor proteins | |
| NImmune Biopharma | Blacksburg | VA | Small Molecules | |
| Noah Medical | San Carlos | CA | Surgical Imaging | |
| Panome Bio | St. Louis | MO | Metabolite, lipid, and protein screening services | |
| Prana Thoracic | Houston | TX | Lung biopsy technology | |
| Rapport Therapeutics | Boston | MA | Precision medicines for neurological disorders | |
| Regencor | San Carlos | CA | Biologic for Heart Regeneration | |
| Resolution Medical | Fridley | MN | Contract Medical Device Manufacturing & Design | |
| ReSuture | Surprise | AZ | Synthetic training models | |
| SanDiegOmics | Del Mar | CA | Sequencing Consultant | |
| Selagine | Chicago | IL | Antibody-based Biologic Eye Drops | |
| Sequilite | Dublin | CA | NGS platform | |
| Shennon Biotechnologies | San Francisco | CA | Proprietary single cell platform to create more effective immunotherapies | |
| Sparian Biosciences | New York | NY | CNS Treatments | |
| Stratus Medical | Magnolia | TX | RF technology for pain | |
| SunMed | Grand Rapids | MI | Respiratory & Anaesthesia Devices | |
| Superior BioDiagnostics | Irvine | CA | Tissue Samples | |
| Switch Therapeutics | South SF | CA | RNAi Therapies | |
| Tiamat Sciences | Durham | NC | Plant-based proteins | |
| Tulex Pharmaceuticals | Cranbury | NJ | Drug Delivery Technology | |
| Ugenome Biotech | Tucson | AZ | Bioinformatics company specializing in additive knowledge for cancer and rare disease | |
| Vaporox | Lone Tree | CO | Wound Care Medical Device | |
| Vernagen | Tucker | GA | mRNA Therapies | |
| ViaDerma | Las Vegas | NV | Topical Antibiotic | |
| Watershed Informatics | Cambridge | MA | Bioinformatics Software | |
| Yatiri Bio | San Diego | CA | Patient matching, outcome predicition | |
| 7 Hills Pharma | Houston | TX | Cancer Immunotherapies | |
| 76Bio | Boston | MA | Targeted Protein Degraders | |
| Accelerated Biosciences | Carlsbad | CA | Human trophoblast stem cells (hTSC) for research | |
| Accord Biopharma | Durham | NC | Specialty Pharma | |
| Be Cool Pharmaceutics | Fairbanks | AK | Small Molecules for brain/spinal cord injury | |
| Adventris Pharmaceuticals | San Francisco | CA | Cancer vaccines | |
| Barrier Biosciences | San Diego | CA | ||
| Iolyx Therapeutics | Bay Area | CA | Immunology and ophthalmalogy | |
| ViaLase | Aliso Viejo | CA | Glaucoma Laser | |
| Profluent | Berkeley | CA | AI Protein Creation | |
| Nexilico | Danville | CA | Computational Biology to Create Microbiome Treatments | |
| United Pharmaceutical | Fullerton | CA | Softgel Manufacturing | |
| Cloudbreak Pharmaceutical | Irvine | CA | Pterygium Treatment | |
| Vulcan Biologics | Irvine | CA | Microbiome modulation platform | |
| Quadriga BioSciences | Los Altos | CA | First-in-class chemotherapeutic agent | |
| TORL BioTherapeutics | Los Angeles | CA | Antibody-drug Conjugate | |
| Fuse Biotherapeutics | Los Angeles | CA | Cell Therapies, Biologics | |
| Y-Trap | Menlo Park | CA | Novel platform of targeted multifunctional immunomodulatory antibody-ligand traps for cancer immunotherapy | |
| NaNotics | Mill Valley | CA | Nanomedicine | |
| Nalo Therapeutics | Palo Alto | CA | Small Molecules | |
| Eysz | Piedmont | CA | Software for Ocular-derived Vitals | |
| Noctrix Health | Pleasanton | CA | Device for restless Leg | |
| MyoGene Bio | San Diego | CA | Gene Editing Treatment | |
| Aspen Biosciences | San Diego | CA | Software solutions for drug discovery and diagnostics challenges | |
| Function Oncology | San Diego | CA | CRISPR-based functional genomics platform | |
| MBrace Therapeutics | San Diego | CA | Phage-display Antibody Discovery, ADCs | |
| Propel Biosciences | Santa Clara | CA | Life science consultancy | |
| VictoGen | Simi Valley | CA | Analytical, Formulation Development, Regulatory | |
| Sagittarius Bio | Thousand Oaks | CA | ||
| OncoVerity | Aurora | CO | Advanced multiomic, data driven patient stratification. Monoclonal Antibody. | |
| Summit Toxicology | Superior | CO | Toxicology, risk assessment and pharmaceutical consulting firm | |
| Neuvotion | Darien | CT | Neurostimulation Therapy | |
| Pangolin Therapeutics | Guilford | CT | Chemistry platform that targets toxic protein mis‑assembly in neurodegenerative and metabolic diseases | |
| New England Cell Therapeutics | New Haven | CT | Cell Therapeutics | |
| PhoenixSongs Biologicals | Branford | CT | Stem Cell Research Models | |
| CytoVeris | Farmington | CT | AI-powered Cancer Imaging | |
| QCDx | Farmington | CT | Detecting and profiling rare cells in the blood circulation | |
| Vanessa Research | Hamden | CT | Treatments for underserved populations | |
| Ananke Therapeutics | Wilmington | DE | RNA Therapeutics | |
| Seven Star Pharmaceutical | Wilmington | DE | solid state chemistry/materials science and engineering principles | |
| Topaz Clinical Research | Apopka | FL | Clinical Research | |
| MLM Biologics | Gainesville | FL | Collagen-based, medical-economic solution for wound closure | |
| TrippBio | Jacksonville | FL | Antivirals | |
| Pharmalab | Miami Lakes | FL | Contract Manufacturing of Liquids & Semi-Solids | |
| Sandhill One | West Palm Beach | FL | API | |
| OXOS Medical | Atlanta | GA | X-ray Technology | |
| Athena Bioscience | Watkinsville | GA | Specialty Pharmaceuticals | |
| NaturemiRI | Solon | IA | MicroRNA Inhibitor System | |
| SynConnection | Buffalo Grove | IL | Contract Research & Manufacturing | |
| Sb Pharma Solutions | Chicago | IL | Medical Affairs Consulting | |
| CTRL Therapeutics | Chicago | IL | Solid Tumor-Infiltrating Lymphocyte | |
| Curatek Pharmaceuticals | Elk Grove Village | IL | Womens Health Treatments | |
| Syenex | Evenston | IL | Synthetic biology platform | |
| OH Pharmaceutical | Oak Brook | IL | Injection Kit, Kegel Exercise Equipment | |
| Eradivir | West Lafayette | IN | Bispecific immunotherapy for viral infections | |
| BioinfoScientist | Louisville | KY | Data consultancy | |
| Carepoint Solutions | Beverly | MA | QA/QC Software | |
| Certego Therapeutics | Boston | MA | Psychiatric disorder therapies | |
| Sisu Pharma | Boston | MA | Compounds Targeting HSF1 | |
| Amasa Therapeutics | Boston | MA | Cell Therapy for Cancer | |
| CILA Therapeutics | Boston | MA | Inhaled therapies for the treatment of Primary Ciliary Dyskinesia | |
| Stylus Medicine | Boston | MA | Therapeutics | |
| ZSFab | Boston | MA | 3D printed surgical implants | |
| Arvada Therapeutics | Brookline | MA | ||
| Resonance Medicine | Cambridge | MA | Drug Development | |
| Vrata Therapeutics | Cambridge | MA | Precision medicines | |
| Bilayer Therapeutics | Cambridge | MA | Bile acid delivered via proprietary bilayer tablet technology | |
| Convergent Therapeutics | Cambridge | MA | Radiotherapies | |
| Edelweiss Immune | Cambridge | MA | ||
| Enable Life Sciences | Cambridge | MA | Pharma Consulting | |
| Matice Biosciences | Cambridge | MA | Peptides for Scar Reduction | |
| SynerK | Concord | MA | RNA-targeted Therapies | |
| ProFoldin | Hudson | MA | Biochemical Assays | |
| Precision Biosystems | Mansfield | MA | Western blot automation | |
| tBrexa | Mansfield | MA | B Reg cells | |
| Oncovolution | Mansfield | MA | Platinum-based chemotherapies | |
| Pharma Models | Marlborough | MA | Preclinical CRO | |
| Courage Therapeutics | Newton | MA | Eating Disorder Treatments | |
| Theranano | Newton | MA | Drug-releasing implants | |
| MedTherapy Biotech | Quincy | MA | Cell, gene & Immunological Therapies | |
| SignaBlok | Shrewsbury | MA | Mechanism-based targeted therapeutics and delivery nanosystems | |
| Snap Dragon Chemistry | Waltham | MA | Process Development & Manufacturing for Fine Chemical Pharmaceuticals | |
| Pulsar Bio | Watertown | MA | DNA Encoded library assays | |
| Nemucore Medical Innovations | Wellesley | MA | Cancer Therapies | |
| Corza Medical | Westwood | MA | Surgical Devices | |
| NyLa Laboratories | Worcester | MA | ||
| PraNa Biosciences | Worcester | MA | Biologics | |
| Fornax Biotech | Worcester | MA | Next-Gen Sequencing | |
| Metro Biotech | Worcester | MA | NAD+ Pharmaceuticals | |
| Newzen Pharma | Parkville | MD | ||
| Rithim Biologics | Woodbinw | MD | Gene Therapy for Tachycardias | |
| Hudson Scientific | Hudson | MI | Contract Manufacturing – device, pharmaceutical | |
| MDI Therapeutics | Novi | MI | Serpin-based therapies | |
| UroDev Medical | Minneapolis | MN | Catheter | |
| Oculus Research | Garner | NC | Clinical Research | |
| Aer Therapeutics | Raleigh | NC | Therapeutic solutions for muco-obstructive lung diseases | |
| Agathos Biologics | Fargo | ND | Biomanufacturing Analytical Services & Technology | |
| Carnegie Pharmaceuticals | Delran | NJ | Generics | |
| Raritan Pharmaceuticals | East Brunswick | NJ | Contract Drug Manufacturing | |
| Unichem Pharmaceuticals | East Brunswick | NJ | Generics | |
| Stira Pharmaceuticals | Fairfield | NJ | Product Development, Analytical R&D | |
| Peplib | Metuchen | NJ | Peptides | |
| VGYAAN Pharmaceuticals | Skillman | NJ | Specialty Pharmaceuticals | |
| Odin Pharmaceuticals | Somerset | NJ | Sterile pharmaceutical company that develops injectable and ophthalmic drugs | |
| Dawah Pharmaceuticals | Totowa | NJ | Injectable & Ophthalmic Generics | |
| Quagen Pharmaceuticals | West Caldwell | NJ | Contract Manufacturing | |
| Phoenix Nest | Brooklyn | NY | Sanfilippo syndrome treatment | |
| Gemini Pharmaceuticals | Commack | NY | Contract Manufacturing & Product Development – OTC | |
| Esper Biosciences | Ithaca | NY | ||
| Delsona Therapeutics | New York | NY | Focused ultrasound imaging technology | |
| PainQx | New York | NY | AI-powered Pain Assessment | |
| Cardiomo Care | New York | NY | Wearable Heart Monitor | |
| Paratus Sciences | New York | NY | Drug Discovery in Bats | |
| Synthis | New York | NY | Immunotherapies | |
| Spirit Pharmaceuticals | Ronkonkoma | NY | OTCs | |
| Avation Medical | Columbus | OH | Wearable Neuromodulation | |
| VintaBio | Philadelphia | PA | Viral Vector Manufacturing | |
| Pharmatrope | Wayne | PA | rHGH | |
| OcyonBio | Aguadilla | PR | Contract Manufacturing | |
| Rhodes Pharmaceutical | Coventry | RI | Generics | |
| Palmetto Pharmaceuticals | Greenville | SC | Generis | |
| Tyler Pharmaceuticals | Cordova | TN | ||
| Theridian Technologies | Austin | TX | Consulting | |
| Attogene | Austin | TX | Rapid Diagnostics | |
| Vida Pharmacal | Spring Branch | TX | Heart Cells as Treatment for Chagas disease | |
| Variant Bio | Seattle | WA | Genomic Drug Discovery | |
| Kinexum | Harpers Ferry | WV | Consulting | |
| StemAxon | Drug development and disease modeling of sporadic Alzheimer’ disease | |||
| 60 Degrees Pharmaceuticals | 60 Degrees Pharmaceuticals | Washington | DC | Specialty Pharmaceuticals |
| Absolute Biotech | Absolute Biotech | Boston | MA | Antibody, reagents, kits |
| Akura Medical | Akura Medical | Los Gatos | CA | Thrombectomy Device |
| Alimentiv | Alimentiv | San Diego | CA | Clinical Services |
| Allos Pharma | Allos Pharma | Honolulu | HI | Fragile X Syndrome and Autism Spectrum Disorder Treatments |
| AmplifiDx | AmplifiDx | Newark | CA | Molecular Diagnostics POC |
| Amplo Biotechnology | Amplo Biotechnology | San Diego | CA | Treatment for congenital myasthenic syndromes |
| AMT Manufacturing Solutions | AMT Manufacturing Solutions | Grand Prairie | TX | Contract Manufacturing |
| Analog Pharma | Analog Pharma | Princeton | NJ | Generics |
| Anew Medical | Anew Medical | Omaha | NE | Neuro therapies |
| Anuncia Medical | Anuncia Medical | Scottsdale | AZ | Cerebrospinal Fluid Flow Device |
| Artelon | Artelon | Marietta | GA | Biomaterial for soft tissue healing |
| Aviko Radiopharmaceuticals | Aviko Radiopharmaceuticals | New York | NY | Radiotherapies |
| BioBoston Consulting | BioBoston Consulting | Boston | MA | Quality & Regulatory Consulting |
| Boston Cell Standards | Boston Cell Standards | Boston | MA | On-slide controls and the only IHC/IF calibrators |
| Confluence Discovery Technologies | Confluence Discovery Technologies | St. Louis | MO | Drug Discovery CRO |
| DirectSync Surgical | DirectSync Surgical | Lawrence | KS | Smart Spinal Implants |
| Domus Diagnostics | Domus Diagnostics | Park City | UT | Test for Infectious Diseases |
| Emboline | Emboline | Santa Cruz | CA | Total Embolic Protection Catheter |
| Endsulin | Endsulin | Madison | WI | Genetic therapy for type 1 diabetes |
| Fe Pharmaceuticals | Fe Pharmaceuticals | Redwood City | CA | Iron-binding Copolymer |
| Flavocure Biotech | Flavocure Biotech | Baltimore | MD | Nature-inspired oncology treatments |
| Genadyne Biotechnologies | Genadyne Biotechnologies | Hicksville | NY | Wound Healing Products |
| Harbor Clinical | Harbor Clinical | Hingham | MA | Clinical Trial Services |
| Hubly Surgical | Hubly Surgical | Lisle | IL | Brain Surgery Drill |
| Hughes Biopharma | Hughes Biopharma | New York | NY | Clinical Development Consultants |
| Initial Therapeutics | Initial Therapeutics | South SF | US | Selective Termination of protein Synthesis Platform |
| Innoblative Designs | Innoblative Designs | Chicago | Il | Electrosurgical Lumpectomy Device |
| Larkspur Biosciences | Larkspur Biosciences | Watertown | MA | Cancer Immunotherapies |
| Metaphore Biotechnologies | Metaphore Biotechnologies | Boston | MA | Therapeutics based on biomimicry |
| Monogram Orthopaedics | Monogram Orthopaedics | Austin | TX | 3D printed implants, robotic surgery |
| Nido Biosciences | Nido Biosciences | Watertown | MA | Small Molecule for Neuro Indications |
| Northeast Biomedical | Northeast Biomedical | Tyngsborough | MA | Medical Device Development |
| NovaXS Biotech | NovaXS Biotech | Chicago | IL | Needle-free Injector |
| Orlucent | Orlucent | Los Gatos | CA | Mole evaluation device |
| Paradigm4 | Paradigm4 | Waltham | MA | Cellular Analytis Software |
| Pattern Bioscience | Pattern Bioscience | Austin | TX | Rapid Diagnosis for Antibiotic Treatment |
| Phlow | Phlow | Richmond | VA | Small Moleculed CDMO |
| Precision Optics | Precision Optics | Gardner | MA | Endoscopes and Optical Devices |
| Promis Diagnostics | Promis Diagnostics | Irvine | CA | Diagnostics |
| ReNAgade | ReNAgade | Cambridge | MA | RNA Drug Delivery |
| Sealonix | Sealonix | Bedford | MA | Hemostatic Sealants |
| Silo Pharma | Silo Pharma | Englewood Cliffs | NJ | Psychedelics |
| Siren Biotechnology | Siren Biotechnology | San Francisco | CA | AAV Immuno-Gene Therapy |
| SIRPant Immunotherapeutics | SIRPant Immunotherapeutics | Hummelstown | PA | Macrophage & T Cell Therapy |
| Tymora Analytical Operations | Tymora Analytical Operations | West Lafayette | IN | Non-invasive Biomarker Discovery |
| Vitalli Bio | Vitalli Bio | Oakland | CA | Immunological disorders |